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Methadone
go.drugbank.com/drugs/DB00333ApprovedInvestigational[A185888,A185891,A185897] Compared with [morphine], the gold standard reference opioid, methadone also acts as an agonist of κ- and σ-opioid receptors, as an antagonist of the N-methyl-D-aspartate (NMDA … It also has a number of unique characteristics that have led to its increased use in the last two decades; in particular, methadone has a lower risk of neuropsychiatric toxicity compared to other opioids
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersProducts: Methasan 10 mg-Tabletten, Methasan 20 mg-TablettenCeftobiprole medocaril
go.drugbank.com/drugs/DB14733ApprovedThe EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole medocaril in February 2010, recommending the refusal of its marketing authorization in the European … [L50467] It received its first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and was subsequently approved in the United States with additional indications
Products: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungRifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnAll of the derivatives have slight different physicochemical properties when compared to the parent structure. … The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid.
Mixtures: RIFETEM 250 MG / 3 ML AMPUL, 50 ADET, RIFOCIN 250 MG+10 MG/3 ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 100 ADETProducts: Rifoxtem 250 mg/3 mL Enjeksiyonluk Çözelti, 50 ADET, RIFOCIN KULAK DAMLASI, 10 ML, %1Albendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Synonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamateInternational brands: Ben-ADutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalDutasteride was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist [tamsulosin] to … trials in androgenetic alopecia.
Mixtures: DUODART 0,5 MG/0,4 MG KAPSÜL,30 KAPSÜL, DUODART 0,5 MG/0,4 MG KAPSÜL,90 KAPSÜLCategories: Drugs Used in Benign Prostatic HypertrophyZinc
go.drugbank.com/drugs/DB01593ApprovedInvestigationalA metallic element of atomic number 30 and atomic weight 65.38. … It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division.
Mixtures: FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 ML, ZİNOMAG 30 MG /300 MG FİLM KAPLI TABLET, 40 ADETSynonyms: ZnFlecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawn[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [L8878,L5056] Flecainide was granted FDA approval on 31 October 1985.[L8875]
Synonyms: N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamideProducts: FLECAINIDE EG, Aristocor 10 mg/ml - InjektionslösungAstemizole
go.drugbank.com/drugs/DB00637ApprovedWithdrawnAstemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. … It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Products: ALMIZOL 10 MG TABLET, 10 ADET, ULKAMIZOL 10 MG TABLET, 10 ADETMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198] … [A180322] Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma
Synonyms: 4-amino-N(10)-methylpteroylglutamic acid, 4-amino-10-methylfolic acidProducts: METOART 10 MG/1 ML ENJ. COZ. ICEREN KULLANIMA HAZIR SIRINGA, METOART 20 MG/2 ML ENJ. COZ. ICEREN KULLANIMA HAZIR SIRINGAPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigationalPioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus. … [A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis.
Mixtures: PIOGLITAZONE E METFORMINA EG, PIOGLITAZONE E METFORMINA EGCategories: Drugs Used in Diabetes