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Quinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigational[A184844] Quinapril was granted FDA approval on 19 November 1991.[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423] … [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Mixtures: ACCUZIDE 20 MG/12.5 MG FILM TABLET, 30 ADET, ACCUZIDE FORT 20 MG/25 MG FILM KAPLI TABLET, 30 ADETCategories: Antihypertensive Agents Indicated for HypertensionGemcitabine
go.drugbank.com/drugs/DB00441ApprovedInvestigationalGemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. … [A233135] Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-oneBupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigational[L6562,A179038,A179050] The combination of naltrexone and bupropion was shown to result in a statistically significant weight loss, with a mean change in body weight of -6.3% compared to -1.3% for placebo … While it has comparable effectiveness to typical first-line options for the treatment of depression such as SSRIs,[A178798,A178804] bupropion is a unique option for the treatment of MDD as it lacks any
Categories: Antidepressive Agents Indicated for DepressionProducts: Bupropion 1A Pharma 150 mg - Tabletten mit veränderter Wirkstofffreisetzung, Bupropion 1A Pharma 300 mg - Tabletten mit veränderter WirkstofffreisetzungDopamine
go.drugbank.com/drugs/DB00988ApprovedInvestigationalDopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Mixtures: INYECCION DE CLORHIDRATO DE DOPAMINA 800 MCG/ML DEXTROSA AL 5% UPS, INYECCION DE CLORHIDRATO DE DOPAMINA EN DEXTROSA AL 5% USP (1600 MCG/ML)Categories: Compounds used in a research, industrial, or household setting, Selective Beta 1-adrenergic AgonistsLamotrigine
go.drugbank.com/drugs/DB00555ApprovedInvestigationalLamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 countries. … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingProducts: LAMOTRIGINA POR 200 MG, Lamotrigin 1A Pharma 5 mg - lösliche TablettenMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalTract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries. … [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: MITOMYCIN-C KYOWA FOR INJECTION 10 mg/vial, MITOMYCIN-C KYOWA 10 MG ENJEKTABL FLAKON, 1 ADETNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalA narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Categories: Heterocyclic Compounds with 4 or More RingsSynonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriolLevomenthol
go.drugbank.com/drugs/DB00825ApprovedInvestigationalMenthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. … Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration
Mixtures: KAMFOLIN 150 MG/G+100 MG/G MERHEM, 50 G, VİCKS İNHALER 415,4 MG + 415,4 MG/1 G BURUN ÇUBUĞUSynonyms: L-menthol, L-(-)-MENTHOLLevosalbutamol
go.drugbank.com/drugs/DB13139ApprovedLevosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). … [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer.
Mixtures: İPRALEV 20 MCG/50 MCG AEROSOL İNHALASYONU,SÜSPANSİYON, 200 DOZProducts: LEVODOSE 100 MG INHALASYON ICIN TOZ ICEREN BLISTER, 60 DOZ, VALBUTYN 1.25 MG/0.5 ML NEBULİZASYON İÇİN TEK DOZLUK İNH. ÇÖZ. İÇEREN FLAKON, 30 ADETCapecitabine
go.drugbank.com/drugs/DB01101ApprovedInvestigationalCapecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexSynonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate