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Propranolol
go.drugbank.com/drugs/DB00571ApprovedInvestigationalPropranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. … [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]
Mixtures: PROPRA COMP RATIOPHARMProducts: Propranolol Hydrochloride Injection USPCarvedilol
go.drugbank.com/drugs/DB01136ApprovedInvestigational[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the … Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.
Products: Apo-Carvedilol 25 mg Tablet USP, Apo-Carvedilol 6.25 mg Tablet USPRemestemcel-L
go.drugbank.com/drugs/DB13973ApprovedInvestigationalWithdrawnRemestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. … [L52008] aGvHD is a T-cell mediated disease that occurs after allogeneic hematopoietic stem cell transplant and is a reaction of donor immune cells against host tissues [A31822] developed by 30-80%
Categories: Stem Cells, Multipotent Stem CellsSynonyms: Adult human mesenchymal stem cells, Allogeneic human mesenchymal stem cellLisinopril
go.drugbank.com/drugs/DB00722ApprovedInvestigational[A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system. … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.
Mixtures: Acelisino comp. semi - Tabletten, Acecomb semi - TablettenSynonyms: [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline, (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-prolineMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]
Mixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5Synonyms: (RS)-MetoprololAtidarsagene autotemcel
go.drugbank.com/drugs/DB17538ApprovedInvestigationalAtidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using
Categories: Autologous Hematopoietic Stem Cell-Based Gene Therapy, Complex MixturesSynonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) geneAllantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalThe concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise [FDA Label]. … Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label].
Mixtures: W15883-CS, Mycellcare iT sProducts: Up and Up Advanced Scar, U-max Multi BBPrednisolone
go.drugbank.com/drugs/DB00860ApprovedInvestigationalVet approvedPrednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.
Categories: Sex Hormones and Insulins, Corticosteroids for Systemic UseProducts: PRED UN, PREDNI 10MG LICHT N KR SUSBetibeglogene autotemcel
go.drugbank.com/drugs/DB16900ApprovedInvestigationalBetibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (β<sup>A-T87Q</sup>-globin) to hematopoietic stem cells in order to treat β-thalassemia. … The use of betibeglogene autotemcel is more effective in patients with β-thalassemia with residual β-globin synthesis (non-β<sup>0</sup>/β<sup>0</sup> genotype) compared to those with no detectable β-globin
Categories: Autologous Hematopoietic Stem Cell-Based Gene Therapy, Complex MixturesLevetiracetam
go.drugbank.com/drugs/DB01202ApprovedInvestigationalIt was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). … Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders.
Products: 6-UR, Levetiracetam Injection USP