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Indapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription … agents may be required in order to achieve blood pressure targets.
Mixtures: BI PRETERAX ® 5.0 MG, PERINDO/IN RAT T 5/1.25Categories: combinations of sulfonamides, Cytochrome P-450 SubstratesVasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigationalVasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation … [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids.
Products: Vasopressin in 0.9% Sodium Chloride, VASOPRESINA 20 UI/MLMepivacaine
go.drugbank.com/drugs/DB00961ApprovedInvestigationalVet approvedA local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. … Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Mixtures: Isocaine HCl Inj 2%, Scandonest 2% Special InjCategories: Heterocyclic Compounds, 1-RingProgesterone
go.drugbank.com/drugs/DB00396ApprovedInvestigationalVet approvedProgesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy. … Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy.
Synonyms: (S)-Pregn-4-en-3,20-dione, (S)-4-Pregnene-3,20-dioneInternational brands: Qi NingAdenosine
go.drugbank.com/drugs/DB00640ApprovedInvestigational[A229833,A229838] Adenosine is also indicated in the treatment of supraventricular tachycardia.[L31998] Adenosine was granted FDA approval on 30 October 1989.[L31978] … The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.
Mixtures: Cellmov Cell Line Mask, Neogen Dermalogy White Truffle Serum In Oi L DropCategories: Antiarrhythmics, Class V, Heterocyclic Compounds, 2-RingCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalIt is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to [DB00169] (vitamin D3) in the skin, which is then converted … Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1-alpha-25-Dihydroxyvitamin D3, 1α,25(OH)2D3Manidipine
go.drugbank.com/drugs/DB09238ApprovedInvestigationalWithdrawnIt is selective for vasculature and does not produce effects on the heart at clinically relevant dosages. … Manidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: MANIDIPINA DOC GENERICI, MANIDIPINA MYLAN GENERICSCefonicid
go.drugbank.com/drugs/DB01328ApprovedIt is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections. … A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995. … [A180826] In addition to the above uses, mycophenolate mofetil has also been studied for the treatment of nephritis and other complications of autoimmune diseases.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateSodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
Mixtures: Gentamicin Sulfate In Nacl O.9% Inj, D5-LRI (5% DEXTROSE IN LOCTATED RINGER'S INJ.)Products: BIO NASAL O.9%, SODIO CLORURO F K I