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Triazolam
go.drugbank.com/drugs/DB00897ApprovedInvestigationalWithdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesNS-2359
go.drugbank.com/drugs/DB05805InvestigationalThis mode of action is expected to produce an optimal reduction in all disease symptoms and the possibility of an earlier onset of action compared to antidepressants already on the market. … Enhancing the function of the three neurotransmitters serotonin, noradrenalin and dopamine, NS2359 has a desired "triple-mode-of-action".
Pexelizumab
go.drugbank.com/drugs/DB04949InvestigationalPexelizumab is a humanized monoclonal antibody used as an immunosuppressive drug. It is being investigated by Alexion Pharmaceuticals.
Categories: Amino Acids, Peptides, and ProteinsSifalimumab
go.drugbank.com/drugs/DB12773InvestigationalThe levels of interferon-alpha are elevated in many patients with active systemic lupus erythematosus (SLE, or lupus) and other autoimmune disorders, and may be associated with disease activity. … Sifalimumab may suppress the abnormal immune activity associated with lupus by binding to multiple interferon-alpha subtypes seen in the serum of lupus patients.
Categories: Amino Acids, Peptides, and ProteinsMDX-1379
go.drugbank.com/drugs/DB05329InvestigationalMDX-1379 vaccine consists of two gp100 melanoma peptides. This drug is underinvestigation to treat malignant melanoma.
Insulin-like growth factor II
go.drugbank.com/drugs/DB14472InvestigationalThe insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. … This factor presents effects related to growth regulation, insulin-like and mitogenic activities.
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsZeaxanthin
go.drugbank.com/drugs/DB11176ApprovedInvestigationalIt gives the distinct yellow color to many vegetables and other plants including paprika, corn, saffron and wolfberries. … As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some micro-organisms.
Fexapotide
go.drugbank.com/drugs/DB05493InvestigationalNX-1207 is an investigational new drug for BPH, whose chemical entity and mechanism of action remain undisclosed.
Categories: Amino Acids, Peptides, and Proteins, Genito Urinary System and Sex HormonesIP501
go.drugbank.com/drugs/DB06450ExperimentalIP-501 is an investigational antifibrotic compound being tested for the treatment of alcohol-induced liver disease and chronic hepatitis-C-induced cirrhosis. … The compound was developed by Indevus Pharmaceuticals.
Technetium Tc-99m ciprofloxacin
go.drugbank.com/drugs/DB05488ExperimentalINFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendicitis and … ciprofloxacin, with Technetium ((99m)Tc), the most commonly used radioisotope in nuclear medical imaging There is currently controversy around the drug's ability to discriminate between sterile inflammation and