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Displaying results 5891 - 5900 of 8974 in total
  1. Drug

    Desmethylprodine

    go.drugbank.com/drugs/DB01478
    ExperimentalIllicit

    It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. Illicit manufacturing has occurred.

  2. Target

    Cytochrome P450 2C8

    go.drugbank.com/bio_entities/BE0002887
    TargetEnzymeHumans

    It is the principal enzyme responsible for the metabolism of the anti-cancer drug paclitaxel (taxol) (PubMed:26427316) … Metabolizes all trans-retinoic acid toward its 4-hydroxylated form (PubMed:11093772).

    Synonyms: Cytochrome P450 form 1
  3. Drug

    TAK-754

    go.drugbank.com/drugs/DB17850
    Investigational

    Developed by Takeda, it is being investigated for the treatment of hemophilia A.[A259831]

  4. Drug

    CXD101

    go.drugbank.com/drugs/DB16182
    Investigational

    CXD101 is under investigation in clinical trial NCT03873025 (A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-cell Lymphoma).

  5. Drug

    Talaporfin

    go.drugbank.com/drugs/DB11812
    Investigational

    Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.

    Categories: Heterocyclic Compounds with 4 or More Rings
  6. Drug

    Actinium Ac 225 dotatate

    go.drugbank.com/drugs/DB23632
    Investigational

    Actinium Ac 225 dotatate is under investigation in clinical trial NCT07150806 (RYZ101 for the Treatment of Progressive or Recurrent Intracranial Meningioma).

  7. Drug

    N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide

    go.drugbank.com/drugs/DB06945
    Experimental

    This compound belongs to the diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups. … This substance is known to target a disintegrin and metalloproteinase with thrombospondin motifs 5.

  8. Drug

    Methadyl acetate

    go.drugbank.com/drugs/DB01433
    ExperimentalIllicit

    A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  9. Drug

    Isothipendyl

    go.drugbank.com/drugs/DB08802
    Investigational

    Isothipendyl is an antihistamine and anticholinergic used as an antipruritic.

    Categories: Antihistamines for Systemic Use, Antihistamines for Topical Use
  10. Drug

    Karaya gum

    go.drugbank.com/drugs/DB10535
    Approved

    Karaya gum allergenic extract is used in allergenic testing.

    Categories: Drugs for Constipation, Compounds used in a research, industrial, or household setting