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Displaying results 5951 - 5960 of 8974 in total
  1. Drug

    SVV-001

    go.drugbank.com/drugs/DB06129
    Investigational

    SVV-001 is investigated for use/treatment in cancer/tumors and lung cancer. SVV-001 is a solid. … SVV-001 (Seneca Valley Virus) is a novel native picornavirus being developed as a systemically deliverable oncolytic virus for treatment of human cancers with neuroendocrine features.

  2. Drug

    Poloxamine 1304

    go.drugbank.com/drugs/DB19167
    Investigational

    Poloxamine 1304 is under investigation in clinical trial NCT00483795 (Pilot Evaluation of Two Multipurpose Solutions in Regards to Corneal Staining).

  3. Pathway

    mTOR Signaling pathway

    smpdb.ca/view/SMP0535455
    Signaling

    mTORC1 via a Rag-independent mechanism requiring the Arf1 GTPase (and Rab1A in a Golgi‑to‑lysosome route) to drive mTORC1 to the lysosome. … Amino acids signal through distinct routes: Leucine binds to CASTOR1 to dissociate it from GATOR2, blocking GATOR1 and enabling RagA/B‑GTP loading to recruit mTORC1 to lysosomes; Arginine is sensed by

    Drugs: Arginine · L-Glutamine · Leucine · ATP · Magnesium cation · Zinc
    Enzymes: Cytosolic arginine sensor for mTORC1 subunit 1
  4. Drug

    EGT-101

    go.drugbank.com/drugs/DB17645
    Experimental

    Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type A.[L45919]

  5. Drug

    Icalcaprant

    go.drugbank.com/drugs/DB21651
    Investigational

    Icalcaprant is under investigation in clinical trial NCT06696755 (A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder … The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist.

  6. Drug

    Aspergillus repens

    go.drugbank.com/drugs/DB10449
    Approved

    Aspergillus repens is a fungus which can provoke allergic reactions. Aspergillus repens extract is used in allergenic testing.

    Mixtures: Number Four Mold Mixture
  7. Drug

    SLx-4090

    go.drugbank.com/drugs/DB05678
    Investigational

    SLx-4090 is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes. [A33218]

  8. Drug

    Relutrigine

    go.drugbank.com/drugs/DB21614
    Investigational

    Relutrigine is under investigation in clinical trial NCT07010471 (A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine).

  9. Drug

    Ginger oil

    go.drugbank.com/drugs/DB14690
    ApprovedInvestigational

    Mixtures: EUGICA FORT
  10. Drug

    Milk thistle

    go.drugbank.com/drugs/DB14375
    ApprovedInvestigational

    Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: EUGICA FORT