Search

Displaying results 51 - 60 of 1841 in total

Drug
Quinethazone
go.drugbank.com/drugs/DB01325
Approved
Quinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Categories: quinethazone and potassium, Sodium Chloride Symporter Inhibitors
Drug
Methyclothiazide
go.drugbank.com/drugs/DB00232
ApprovedWithdrawn
A thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Categories: methyclothiazide and potassium, Sodium Chloride Symporter Inhibitors
Drug
Lubiprostone
go.drugbank.com/drugs/DB01046
ApprovedInvestigational
A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. … Activation of these channels promotes the secretion of a chloride-rich fluid that soften the stool, increase gastrointestinal motility, and induce spontaneous bowel movements (SBM).
Categories: Chloride Channel Agonists
Drug
Chlorothiazide
go.drugbank.com/drugs/DB00880
ApprovedInvestigationalVet approved
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Categories: chlorothiazide and potassium, Sodium Chloride Symporter Inhibitors
Drug
Bendroflumethiazide
go.drugbank.com/drugs/DB00436
ApprovedInvestigational
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 3...
Categories: Sodium Chloride Symporter Inhibitors, bendroflumethiazide and potassium
Drug
Polythiazide
go.drugbank.com/drugs/DB01324
Approved
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Categories: polythiazide and potassium, Sodium Chloride Symporter Inhibitors
Drug
Amiloride
go.drugbank.com/drugs/DB00594
ApprovedInvestigational
Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss.
Categories: Potassium-Sparing Diuretics
Drug
Furosemide
go.drugbank.com/drugs/DB00695
ApprovedInvestigationalVet approved
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestiv...
Categories: Sodium Potassium Chloride Symporter Inhibitors, furosemide and potassium
Drug
Bumetanide
go.drugbank.com/drugs/DB00887
ApprovedInvestigational
Bumetanide is a sulfamyl diuretic.
Categories: Sodium Potassium Chloride Symporter Inhibitors, bumetanide and potassium
Drug
Hydroflumethiazide
go.drugbank.com/drugs/DB00774
ApprovedWithdrawn
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
Categories: hydroflumethiazide and potassium, Sodium Chloride Symporter Inhibitors