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Glycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approvedGlycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergi...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: GLYCO-P, Glyrx-PFOlopatadine
go.drugbank.com/drugs/DB00768ApprovedOlopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine work...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: OLODINA PF®, OLOFTAL PF®Paclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedPaclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree whi...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: PAXUS PM (30 MG), PAXUS PM (100 MG)Lacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigationalLacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of intera...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Lacasa 50 Lacosamide Film Coated Tablets Ph. Eur. 50 mg, Lacasa 100 Lacosamide Film Coated Tablets Ph. Eur. 100 mgImipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalImipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In...
International brands: Depsonil-PMCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigationalValproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a centur...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: VALHEL PR 300MG, VALHEL PR 500MGRisedronic acid
go.drugbank.com/drugs/DB00884ApprovedInvestigationalRisedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label] . It functions by preventing resorption of bone[FDA Label] .
Products: RISEDRONSAEURE 1A PH 35MG, RISEDRONSAEURE 1A PH 75MGLevocarnitine
go.drugbank.com/drugs/DB00583ApprovedInvestigationalConstituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Products: GNC PP L-Carnitine 500 mgPancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigationalPancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-J...
Products: KREON 35000 PH EUR LIP EIAcyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigationalAcyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and so...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ACIC 250 PI VIA, ACIC 500 PI VIA