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Tagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigationalTagraxofusp is a CD123-directed cytotoxin. It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in Escherichia co...
Synonyms: Diphtheria toxin-il-3 fusion protein targeting IL-3 receptorSatralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigationaluntil it reaches an endosome, after which the drug may dissociate from the receptor and move back into the plasma to act again. … uniquely formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors occurs in a pH-dependent manner[A218551] - this allows satralizumab to bind an IL-6 receptor
Categories: Interleukin-6 Receptor AntagonistSynonyms: Humanised anti-IL-6 receptor monoclonal antibodyWitch hazel
go.drugbank.com/drugs/DB11111ApprovedInvestigationalNutraceuticalProducts: Bien Vita Moor Cell Mask, Vita Brightening Renewal MaskOveractive Bladder Syndrome (OABS)
go.drugbank.com/conditions/DBCOND0036138Drugs: Botulinum toxin type A · Darifenacin · Fesoterodine · Imidafenacin · Mirabegron · Oxybutynin +3 moreSynonyms: Over-Active Bladder, Over Active BladderNipocalimab
go.drugbank.com/drugs/DB16257ApprovedInvestigationalNipocalimab-aahu is a neonatal Fc receptor (FcRn) blocker used to treat certain antibody-mediated autoimmune diseases.
Synonyms: immunoglobulin G1-lambda, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], Homo sapiens monoclonal, Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimerCategories: Neonatal Fc Receptor BlockerTividenofusp alfa
go.drugbank.com/drugs/DB17628ApprovedInvestigationalTividenofusp alfa is a recombinant human IDS fused to a monoclonal antibody that targets the human insulin receptor (HIR), utilizing receptor-mediated transcytosis to gain access to the central nervous
Synonyms: - L-iduronate sulfate sulfatase, EC:3.1.6.13) pro-protein (1-525), fused via the peptide linker 526 GGGGS 530 to a human immunoglobulin G1 C-terminal Fc fragment (531-757) variant (L 544>A, L 545>A, T, ENZYME TRANSPORT VEHICLE SPECIFIC FOR THE TRANSFERRIN RECEPTOR FUSED TO IDURONATE 2-SULFATASEOvereating
go.drugbank.com/conditions/DBCOND0060464Drugs: HemicellulaseSynonyms: Over Eating, Over-eatingCT-001
go.drugbank.com/drugs/DB18284InvestigationalSynonyms: Human recombinant factor VIIa variant (P10Q, K32E, T106N, V253N), desialylated