Search
Digoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigationalDigoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: LANOXIN PG 62.5MCG TABLETS, LANOXIN-PG PAEDIATRIC/GERIATRIC TABLET 0.0625 mgArbutin
go.drugbank.com/drugs/DB11217ApprovedExtracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal di...
Mixtures: The Prestige BB SPF25 PA 2Plus, Absolute Total BB SPF37 PA 3PlusSynonyms: p-hydroxyphenyl β-D-glucoside, p-hydroxyphenyl β-D-glucopyranosideDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: Cosopt PF, Cosopt PFCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalRivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Ixobran 15 (Rivaroxaban Tablet Ph Eur 15mg), Ixobran 10 (Rivaroxaban Tablet Ph Eur 10mg)Celecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigationalCelecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptom...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamideCarvedilol
go.drugbank.com/drugs/DB01136ApprovedInvestigationalCarvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. It is currently used to treat heart failure, left ventricular dysfunct...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: CARVEDILOL HEU 25MG NET, CARVEDILOL HEU 12.5MG NETHydroquinone
go.drugbank.com/drugs/DB09526ApprovedInvestigationalHydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It...
Synonyms: p-Benzenediol, p-HydroquinoneProducts: NEXT GENERATION Correct Brightening Serum, Aclaro PD HydroquinoneNitroprusside
go.drugbank.com/drugs/DB00325ApprovedInvestigationalNitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing...
Products: H0-P3Telmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinit...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: TELMISARTAN HEU 20MG NET, TELMISARTAN HEU 40MG NETAzathioprine
go.drugbank.com/drugs/DB00993ApprovedInvestigationalAzathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index. Azathioprine is us...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: AZATHIOPRIN HEU 50MG NET