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Doxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approvedDoxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]
Synonyms: Doxycycline, Anhydrous doxycyclineInternational brands: Nu-DoxycyclineDoxycycline Action Pathway
smpdb.ca/view/SMP0000291Drug actionDoxycycline is a long-acting tetracycline derived from oxytetracycline. Like minocycline, it is lipophilic and can diffuse through the lipid bilayer of bacteria. … Doxycycline reversibly binds to the bacterial 30S ribosomal subunit and to a lesser extent the 50S subunit, blocking the binding of aminoacyl tRNA to the A site on the ribosome-RNA complex.
Drugs: DoxycyclineDoxycycline Predicted Metabolism Pathway
smpdb.ca/view/SMP0174526MetabolicMetabolites of Doxycycline are predicted with biotransformer.
Doxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigationalDoxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasti...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: DOXAZOSIN 1 HEUMANN NET, DOXAZOSIN 2 HEUMANN NETZinc acetate
go.drugbank.com/drugs/DB14487ApprovedInvestigationalProducts: Neat 3B Baby B, Neat 3B Senior BRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 b...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROPINIROL HEU 2 MG RET NET, ROPINIROL HEU 4 MG RET NETD-glucose
go.drugbank.com/drugs/DB01914ApprovedInvestigationalVet approvedGlucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It c...
Mixtures: Isolyte P in Dextrose, DIANEAL PD-2 with DextroseProducts: DEXTROSE INJ 5% BP (1000ML P/C), NEOFLEKS %10 DEKSTROZ SUDAKI ÇÖZELTİSİ 100 ML PP TORBA SETLIBimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigationalBimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution an...
Mixtures: GANFORT PF, GANFORT PF Eye DropsCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTriclocarban
go.drugbank.com/drugs/DB11155ApprovedTriclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacteri...
Products: NEXT 1 Anti-bacterial, Next 1 Anti-Bacterial SportMoxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnMoxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, AC...
Products: MOXONIDIN HEU 0.2MG NET, MOXONIDIN HEU 0.3MG NET