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Selumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigationalThe novel MEK 1/2 inhibitor, selumetinib, was initially approved solely for the treatment of pediatric patients with Neurofibromatosis type 1 (NF-1) and symptomatic, inoperable plexiform neurofibromas (PN … NF-1 is considered rare, with an estimated incidence of 1/3000 individuals.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCilgavimab
go.drugbank.com/drugs/DB16393ApprovedInvestigationalhamster ovary (CHO) cells derived from a neutralizing antibody isolated from a patient with a natural history of SARS-CoV-2 infection and modified through targeted amino acid substitutions to exhibit an … Cilgavimab, in combination with [tixagevimab], was issued an FDA emergency use authorization (EUA) on December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for
Tixagevimab
go.drugbank.com/drugs/DB16394ApprovedInvestigationalhamster ovary (CHO) cells derived from a neutralizing antibody isolated from a patient with a natural history of SARS-CoV-2 infection and modified through targeted amino acid substitutions to exhibit an … Tixagevimab, in combination with [cilgavimab], was issued an FDA emergency use authorization (EUA) on December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for
Thonzylamine
go.drugbank.com/drugs/DB11235ApprovedThonzylamine is an antihistamine and anticholinergic drug.
Mixtures: Poly-Hist DM, Nasopen PESulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawnSulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher d...
Mixtures: NEUPAX DUO-SCategories: P-glycoprotein substrates, Dopamine D2 Receptor AntagonistsAprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnThe goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery.
Mixtures: TISSEEL FIBRIN SEALANT VH S/D (FROZEN), SAN. VE TİC. LTD.Carbinoxamine
go.drugbank.com/drugs/DB00748ApprovedThe product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many … carbinoxamine-containing preparations contained inappropriate labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and the use in children under 2 years of age), which can
Mixtures: Coldec DS, Rondamine DMSynonyms: 2-(p-chloro-α-(2-(dimethylamino)ethoxy)benzyl)pyridineEnzacamene
go.drugbank.com/drugs/DB11219ApprovedCommonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. … While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and cosmetic products is approved by Health Canada.
Mixtures: Bain De Soleil Protection Lotion SPF 15, Secret Key Natural Cc Cushion Spf50 Pa / 02 Natural CcSynonyms: 3-(p-Methylbenzylidene)-DL-camphor, Enzacamene D-L formFenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnIt is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency. … Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity.
Products: P.Tyrosine
go.drugbank.com/drugs/DB00135ApprovedInvestigationalNutraceuticalTyrosine is a non-essential amino acid. In animals it is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.
Synonyms: (S)-3-(p-Hydroxyphenyl)alanine, (−)-α-amino-p-hydroxyhydrocinnamic acidMixtures: Appformin-D, Appbutamone-D