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Displaying results 591 - 600 of 10000 in total
  1. Drug

    Etoposide

    go.drugbank.com/drugs/DB00773
    ApprovedInvestigational

    Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. … A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.

    Synonyms: 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside), 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-oneProducts: EPOSIN CONCENTRADO PARA SOLUCION DE INFUSION DE 20 MG/ML, INJECTION ETOPOSIDE CS 100MG IN 5ML
  2. Drug

    Glyburide

    go.drugbank.com/drugs/DB01016
    ApprovedInvestigational

    [A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120] … [L8123] Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and calcium ion concentrations.

    Mixtures: DUO-ANGLUCID, MELLIMET G ® TABLETAS RECUBIERTAS CON PELÍCULA 500MG + 2.5 MGCategories: Drugs Used in Diabetes
  3. Drug

    Cephalexin

    go.drugbank.com/drugs/DB00567
    ApprovedInvestigationalVet approved

    [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971. … Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide.

    Synonyms: 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid, 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acidProducts: Nu-cephalex Tab 500mg, Nu-cephalex Tab 250mg
  4. Drug

    Clonazepam

    go.drugbank.com/drugs/DB01068
    ApprovedIllicitInvestigational

    in the treatment of the aforementioned medical conditions. … [FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.

    Synonyms: 5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one, 1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-oneProducts: RIVOTRIL ® TABLETAS DE 2.0 MG.
  5. Drug

    Tolterodine

    go.drugbank.com/drugs/DB01036
    ApprovedInvestigational

    Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.

    Products: TOXTREX 4 MG CÁPSULAS DE LIBERACIÓN EXTENDIDA, TOXTREX® 2 MG CÁPSULAS DE LIBERACIÓN EXTENDIDA
  6. Indication

    Facial rash

    go.drugbank.com/conditions/DBCOND0098014
    Drugs: Zinc oxide
    Synonyms: Rash on face
  7. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis. … [A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood.

    Products: D-FUMARIC 240 CAPSULAS DE LIBERACIÓN RETARDADA 240 MG, D-FUMARIC 120 CAPSULAS DE LIBERACION RETARDADA 120 MG
  8. Drug

    Trimebutine

    go.drugbank.com/drugs/DB09089
    ApprovedInvestigational

    It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders [A19691]. … Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.

    International brands: Ni Wei Fu, Shuang DiProducts: COLYPAN ®300 MG TABLETAS DE LIBERACION PROLONGADA, TRIMEBUTINA MALEATO 300 MG TABLETA DE LIBERACIÓN PROLONGADA
  9. Drug

    Etofenamate

    go.drugbank.com/drugs/DB08984
    Investigational

    It is a non-steroidal anti-inflammatory drug (NSAID).

    Categories: Analgesics, Non-Narcotic, Non COX-2 selective NSAIDSProducts: INDOREX-SAN
  10. Drug

    mRNA-1283

    go.drugbank.com/drugs/DB22668
    ApprovedInvestigational

    mRNA-1283 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant lineage JN.1. … [L53408] As opposed to previously approved COVID-19 mRNA vaccines, including the original [Moderna COVID-19 Vaccine], mRNA-1283 encodes only the immunodominant regions (NTD and RBD) of the SARS-CoV-