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ARX201
go.drugbank.com/drugs/DB05082Investigational(PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino acid (ahGH). … ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol
JB991
go.drugbank.com/drugs/DB05081ExperimentalThe drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro. … In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug will be applied topically on the skin.
Tirapazamine
go.drugbank.com/drugs/DB04858InvestigationalTirapazamine entered phase III testing in 2006 for patients with head and neck cancer and gynecological cancer, as well as for other solid tumor cancer types. … Tirapazamine, also known as SR-4233, is an experimental anticancer drug that is activated in hypoxic conditions.
Dengue virus serotype 1
go.drugbank.com/drugs/DB22664Approved[A274008] It is one of four serotypes covered by Qdenga, a live, attenuated, tetravalent vaccine used for the prevention of dengue disease.
Cerulenin
go.drugbank.com/drugs/DB01034ExperimentalCerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. … It is also shown to inhibit feeding and induce dramatic weight loss in mice. It is found naturally in the Cephalosporium caerulensfungus.
AZD-8848
go.drugbank.com/drugs/DB14868InvestigationalAZD-8848 is under investigation in clinical trial NCT01818869 (To Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses AZD8848 in Healthy Subjects).
Categories: Nucleic Acids, Nucleotides, and NucleosidesPradofloxacin
go.drugbank.com/drugs/DB11453ExperimentalVet approvedIt was approved by the European Commission in April 2011 for bacterial infections in dogs and cats. … Pradofloxacin is a 3rd generation fluoroquinolone antibiotic developed by Bayer HealthCare AG, Animal Health GmBH.
Danegaptide
go.drugbank.com/drugs/DB11821InvestigationalDanegaptide has been investigated for the treatment of Focus of Study is STEMI.
Categories: Amino Acids, Peptides, and ProteinsDirlotapide
go.drugbank.com/drugs/DB11399InvestigationalVet approvedIt is marketed by Pfizer and Zoetis under the brand name, _Slentrol_, and is not intended for human use.