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Daprodustat
go.drugbank.com/drugs/DB11682ApprovedInvestigationalDaprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK. … [L44963] The drug is currently under EMA review.
Synonyms: Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)-Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingIferanserin
go.drugbank.com/drugs/DB11686InvestigationalIferanserin has been investigated for the treatment of Hemorrhoids.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor Antagonists2-chloroethyl-3-sarcosinamide-1-nitrosourea
go.drugbank.com/drugs/DB11688Investigational2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific
Synonyms: 2-chloroethyl-3-sarcosinamide-1-nitrosourea, ACETAMIDE, 2-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)METHYLAMINO)-Ilorasertib
go.drugbank.com/drugs/DB11694InvestigationalIlorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Synonyms: 1-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea, 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl)urea)Categories: Heterocyclic Compounds, 1-RingIpragliflozin
go.drugbank.com/drugs/DB11698InvestigationalIpragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Categories: Heterocyclic Compounds, 1-Ring, Sodium-Glucose Transporter 2 InhibitorsAdomeglivant
go.drugbank.com/drugs/DB11704InvestigationalAdomeglivant has been investigated for the basic science of Type 2 Diabetes.
Peficitinib
go.drugbank.com/drugs/DB11708InvestigationalPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
Categories: Heterocyclic Compounds, 1-RingDutogliptin
go.drugbank.com/drugs/DB11723InvestigationalDutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Ipatasertib
go.drugbank.com/drugs/DB11743InvestigationalIpatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.
Categories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-akt, antagonists & inhibitorsBryostatin 1
go.drugbank.com/drugs/DB11752InvestigationalBryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.
Synonyms: Bryostatin 1, Bryostatin-1Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors