Bryostatin 1

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DB11752InvestigationalSmall molecule

Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.

Mechanism: Pharmacologically active on Protein kinase C epsilon type
Curator reviewed
Formula / weight: C₄₇H₆₈O₁₇ · 905.044 g/mol (avg)
Also known as: Bryostatin-1

Resolves to

Compound

UNII37O2X55Y9ECAS83314-01-6ChEMBLCHEMBL449158ChEBI88353PubChem22524140

Structure

InChIKeyMJQUEDHRCUIRLF-TVIXENOKSA-NSMILES

[H][C@]12C[C@H](OC(C)=O)C(C)(C)[C@](O)(C[C@]3([H])C\C(C[C@@]([H])(O3)\C=C\C(C)(C)[C@]3(O)O[C@@]([H])(C\C(=C/C(=O)OC)[C@@H]3OC(=O)\C=C\C=C\CCC)C[C@@]([H])(OC(=O)C[C@H](O)C1)[C@@H](C)O)=C\C(=O)OC)O2

Targets

Q02156PRKCEP17252PRKCAQ14790CASP8Q15139PRKD1P42081CD86P35354PTGS2P24385CCND1P01375TNF+1 more

What you can answer from here — as of April 02, 2025

9Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

323Drug interactionsStructured to mechanism, not free text

35Clinical trialsPhase, status and sponsor resolved per trial

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Bryostatin 1, and which of those have an active Phase 3 trial?

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