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Displaying results 6031 - 6040 of 8974 in total
  1. Drug

    Isatoribine

    go.drugbank.com/drugs/DB04860
    Experimental

    Isatoribine is a selective agonist of TLR7.

    Synonyms: 7-TOG
  2. Drug

    VX-702

    go.drugbank.com/drugs/DB05470
    Investigational

    In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA. … VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor.

  3. Drug

    G17DT Immunogen

    go.drugbank.com/drugs/DB04914
    Investigational

    It is also in a phase II/III trial for advanced stomach cancer in combination with 5-fluorouracil and cisplatin and in a late phase II trial for advanced colorectal cancer in combination with irinotecan … It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine.

  4. Drug

    Penicillium expansum

    go.drugbank.com/drugs/DB10810
    Approved

    Penicillium expansum is a fungus which can provoke allergic reactions. Penicillium expansum extract is used in allergenic testing.

    Mixtures: Number Four Mold Mixture
  5. Drug

    SPC2968

    go.drugbank.com/drugs/DB06351
    Investigational

    It was under investigation in clinical trial NCT02564614 (A Study of Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic Acid (mRNA) Antagonist (RO7070179), to Demonstrate Proof-of-mechanism in Adult

  6. Drug

    Toluene

    go.drugbank.com/drugs/DB11558
    InvestigationalVet approved

    It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    PX-478

    go.drugbank.com/drugs/DB06082
    Investigational

    PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. PX-478 was effective in models of both non-small cell lung cancer and ...

  8. Drug

    Octopamine

    go.drugbank.com/drugs/DB13251
    Experimental

    Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.

  9. Drug

    Mepiprazole

    go.drugbank.com/drugs/DB09197
    Experimental

    Mepiprazole is marketed in Spain for the treatment of anxiety neuroses. … It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and has also been shown to inhibit the reuptake and induce the release of serotonin, dopamine, and norepinephrine to varying extents.

  10. Drug

    Transfluthrin

    go.drugbank.com/drugs/DB15117
    Investigational

    Transfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).

    Categories: Compounds used in a research, industrial, or household setting