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Displaying results 6031 - 6040 of 10000 in total
  1. Drug

    RGX-501

    go.drugbank.com/drugs/DB17639
    Investigational

    RGX-501 is an adeno-associated virus vector 8 (AAV8)-mediated gene therapy that delivers a functional copy of the human low-density lipoprotein receptor (LDLR) gene to liver cells. … It is being investigated for the treatment of homozygous familial hypercholesterolemia.[L46696]

  2. Drug

    Seltorexant

    go.drugbank.com/drugs/DB14961
    Investigational

    Seltorexant is under investigation in clinical trial NCT03494907 (A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants).

  3. Drug

    Litoxetine

    go.drugbank.com/drugs/DB15038
    Investigational

    Litoxetine is under investigation in clinical trial NCT03397771 (DBPC Trial to Evaluate the Safety, Tolerability and Efficacy of Oral Litoxetine in Subjects With Urinary Incontinence).

  4. Drug

    Ongericimab

    go.drugbank.com/drugs/DB18949
    Investigational

    Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (Hefh).).

  5. Drug

    Suplatast

    go.drugbank.com/drugs/DB19138
    Investigational

    Suplatast is under investigation in clinical trial NCT05983471 (Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF)).

  6. Drug

    KT-A261

    go.drugbank.com/drugs/DB19317
    Experimental

    KT-A261 is an adeno-associated viral vector serotype 2 (AAV2) encoded to express adalimumab. It is being investigated for the treatment of noninfectious uveitis.

  7. Drug

    Alvespimycin

    go.drugbank.com/drugs/DB12442
    Investigational

    In comparison to the first HSP90 inhibitor tanespimycin, it exhibits some pharmacologically desirable properties such as reduced metabolic liability, lower plasma protein binding, increased water solubility … It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent.

  8. Drug

    MKC1106-PP

    go.drugbank.com/drugs/DB06030
    Experimental

    The plasmid portion is a recombinant plasmid expressing segments of the 2 target antigens, PRAME and PSMA. … MKC1106-PP is a 3-component investigational vaccine made up of a DNA plasmid (pPRA-PSM) and 2 peptides E-PRA and E-PSM.

  9. Drug

    Gridegalutamide

    go.drugbank.com/drugs/DB21593
    Investigational

    The usage of the INN stem '-lutamide' in the name indicates that Gridegalutamide is a non-steroid antiandrogen. … Gridegalutamide is under investigation in clinical trial NCT04428788 (Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer).

  10. Drug

    Tamuzimod

    go.drugbank.com/drugs/DB21621
    Investigational

    The usage of the INN stem '-imod' in the name indicates that Tamuzimod is a immunomodulator, both stimulant/suppressive and stimulant. … Tamuzimod is under investigation in clinical trial NCT05156125 (VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis).