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(7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acid
go.drugbank.com/drugs/DB03970ExperimentalSynonyms: (7R)-7-(6,7-Dihydro-5H-cyclopenta[d]imidazo[2,1-b][1,3]thiazol-2-yl)-2,7-dihydro-1,4-thiazepine-3,6-dicarboxylic acidRaltitrexed
go.drugbank.com/drugs/DB00293ApprovedInvestigationalRaltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingProducts: TOMUDEX ® 2 MG, TOMUDEX 2 MG FLAKON, 1 ADETGuaifenesin
go.drugbank.com/drugs/DB00874ApprovedInvestigationalVet approvedAfter the negotiation between FDA and major manufacturers, a voluntary transition of labels for not using guaifenesin in children under the age of 4 years was endorsed by FDA in 2008 [F4525]. … to be safe and effective in children under the age of 6 years [F4525].
Mixtures: RINOGEST EKSPEKTORAN 30 MG / 5 ML + 100 MG / 5 ML ŞURUP, 150 ML, N-ACETILCISTEÍNA 2 G + GUAYACOLATO DE GLICERILO 2 G JARABEInternational brands: Duratuss GSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIt is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OBESTOP® 10 MG CAPSULAS, OBESTOPPOR 5 MG CAPSULASPaclitaxel docosahexaenoic acid
go.drugbank.com/drugs/DB05297InvestigationalA combination of [docosahexaenoic Acid] (a natural fatty acid) and [paclitaxel] (an anticancer drug) being studied in the treatment of cancer. It is a type of mitotic inhibitor.
Synonyms: Paclitaxel 2'-(all-cis-4,7,10,13,16,19-docosahexaenoate)Simethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigationalSimethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. … [A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308]
Mixtures: NOAX 3, BROMUX D® 100/300 MG CÁPSULA.Categories: Compounds used in a research, industrial, or household settingZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.
Mixtures: N/A, LAVUZID® NCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesPhenylacetylglutamine
go.drugbank.com/drugs/DB17167ExperimentalSynonyms: Antineoplaston as 2-1 component phenylacetylglutamine, L-glutamine, n2-(phenylacetyl)-TRK-001
go.drugbank.com/drugs/DB18577InvestigationalTRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Synonyms: Natural Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and Transforming Growth Factor-beta