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Cyclopentamine
go.drugbank.com/drugs/DB08999ApprovedWithdrawnCyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. … It has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.
Ulobetasol
go.drugbank.com/drugs/DB00596Approved[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047] … [A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.
Brimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. … [A178948] The topical form of brimonidine was approved by the FDA in August 2013 for the symptomatic treatment of persistent facial erythema of rosacea in adults.
Mixtures: Combigan 2 mg/ml + 5 mg/ml Augentropfen, SIMBRINZA EYE DROPS, SUSPENSION 10 MG/ML + 2 MG/MLProducts: BRIMONIDINA EG, MIRVASO GEL 3MG/GKetoconazole
go.drugbank.com/drugs/DB01026ApprovedInvestigational[A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole] and [clotrimazole], due to its broad spectrum and good absorption. … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.
Mixtures: CLINDAMICINA/KETOCONAZOL 100 MG/400MGCategories: combinations of imidazole derivatives, Metabolic Side Effects of Drugs and SubstancesLiotrix
go.drugbank.com/drugs/DB01583ApprovedIt is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues. … In fact, administration of T3 may result in supratherapeutic levels of T3.
Ribociclib
go.drugbank.com/drugs/DB11730ApprovedInvestigationalThese proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Ribociclib was approved by the FDA in March 2017 under the brand name Kisqali. … Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6).
Products: KISQALI (200 MG), KISQALI 200 MG TABLETAS RECUBIERTASClobetasol propionate
go.drugbank.com/drugs/DB01013ApprovedInvestigational[A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809]
Products: DERMOSOL CREAM 0.5 mg/g, CLONOVATE CREAM 0.05 g/100 gRacepinephrine
go.drugbank.com/drugs/DB11124ApprovedIt is an active ingredient in oral inhalation over-the-counter products as racepinephrine hydrochloride. … It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath.
Cedazuridine
go.drugbank.com/drugs/DB15694ApprovedInvestigational[A215082, A215092, A215097] Hypomethylating agents such as [decitabine] and [azacitidine] are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous cells. … Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated
Ziconotide
go.drugbank.com/drugs/DB06283ApprovedInvestigationalZiconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ comprising 25 amino acids with three disulphide bonds. … synthesized without loss of proper bond formation or structural elements.
Categories: Compounds used in a research, industrial, or household setting