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Timolumab
go.drugbank.com/drugs/DB18597InvestigationalTimolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Synonyms: recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1)Docetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676] Compared to paclitaxel, docetaxel is two times more potent as an inhibitor of microtubule depolymerization. Docetaxel binds to microtubules but does not interact with dimeric tubulin.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: TAXOTERE VIAL X 20 MG, TAXOTERE® VIAL X 80 MGPinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalIt is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function.
Mixtures: DICETEL-DUO, DICETEL® DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesQuinapril
go.drugbank.com/drugs/DB00881ApprovedInvestigationalQuinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat. It is used to treat hypertension and heart failure. ACE inhibitors are commonly used as a first line therapy in the treatment...
Products: ACCUPRIL® TABLETA RECUBIERTA DE 20 MGMycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigational[A249175] This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. … [A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: Mar-mycophenolic Acid, MICOFENOLATO DE MOFETILOBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalBaclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasti...
Synonyms: DL-4-Amino-3-p-chlorophenylbutanoic acid, DL-BaclofenInternational brands: Nu-BaclofenOxymetazoline
go.drugbank.com/drugs/DB00935ApprovedInvestigationalOxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors. … [L15062] As an effective decongestant, oxymetazoline is available in over-the-counter intranasal sprays used to relieve nasal and sinus congestion caused by a wide variety of conditions, such as common
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesProducts: Nasal D, DG Health NasalLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Mixtures: Dg Health Anti Diarrheal Anti GasCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approved[L6748] Opioid overdoses kill an average of 11 Canadians daily.[L6751] Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: DUROGESIC D-TRANS, FENTANIL HEXAL AGTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.
Mixtures: Van-telmisartan-hctz, Van-telmisartan-hctzCategories: P-glycoprotein inhibitors, Cytochrome P-450 Enzyme Inhibitors