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Nicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is also important medically because of its presence in tobacco smoke. … It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceSynonyms: 3-(2-(N-methylpyrrolidinyl))pyridine, (S)-3-(N-methylpyrrolidin-2-yl)pyridineChlorpheniramine
go.drugbank.com/drugs/DB01114ApprovedInvestigationalA histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. … One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Mixtures: KATARIN 120 MG+50 MG+1 MG/5 ML PEDIATRIK SURUP 100 ML, DEFLU 24/0.2/0.5 mg/ml ŞURUP, 100 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsNaltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedDerivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction.
Mixtures: Troxyca ER, Troxyca ERCategories: Heterocyclic Compounds with 4 or More Rings, Drugs Used in Alcohol DependenceVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalreceptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. … Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional
Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT1 Receptor AntagonistsProducts: SORDENA 10 MG FİLM KAPLI TABLET , 28 ADET, VORTİNELLİX 10 MG FİLM KAPLI TABLET , 28 ADETMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approvedAs the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: MGAValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalwith type 2 diabetes and in nondiabetic patients diagnosed with chronic kidney disease. … The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized.
Mixtures: ONEPTUS 24 MG/26 MG FILM KAPLI TABLET, 28 ADET, ENTRESTO 50 MGCategories: Angiotensin 2 Receptor Blocker, Agents Acting on the Renin-Angiotensin SystemLatanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigationalIt was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse effects like other drugs used to treat elevated intraocular pressure, such as [Timolol].
Mixtures: Xalacom 50 Mikrogramm/ml + 5 mg/ml Augentropfen, LatanoTim-Vision 50 Mikrogramm/ml + 5 mg/ml AugentropfenCategories: Compounds used in a research, industrial, or household settingFerric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigational[L11581,L11587] Clinical trials show that it is non-inferior to [iron sucrose], another form of iron that is often administered in iron deficiency, and less likely to cause serious hypersensitivity that … Though it is generally considered non life-threatening, iron deficiency may considerably affect quality of life.
Products: Diafer 50 mg/ml Injektionslösung, Monofer 100 mg/ml solution for injection/infusion in vialsBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalIt was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough.
Mixtures: PENBRITIN EX, BRONCODEX JARABE (GUAIFENESIN 2 G + BROMHEXINA HCI 0.08 G)Synonyms: N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, 3,5-dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamineTelmisartan
go.drugbank.com/drugs/DB00966ApprovedInvestigationalTelmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. … smooth muscle, ultimately leading to a reduction in arterial blood pressure.
Mixtures: TWYNSTA 80/10 MG TABLET, 28 ADET, TELMODIP 80 MG/10 MG TABLET, TABLET, 28 ADETCategories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor Blocker