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Ipragliflozin
go.drugbank.com/drugs/DB11698InvestigationalIpragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Categories: Heterocyclic Compounds, 1-Ring, Sodium-Glucose Transporter 2 InhibitorsAdomeglivant
go.drugbank.com/drugs/DB11704InvestigationalAdomeglivant has been investigated for the basic science of Type 2 Diabetes.
Peficitinib
go.drugbank.com/drugs/DB11708InvestigationalPeficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
Categories: Heterocyclic Compounds, 1-RingDutogliptin
go.drugbank.com/drugs/DB11723InvestigationalDutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Ipatasertib
go.drugbank.com/drugs/DB11743InvestigationalIpatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.
Categories: Heterocyclic Compounds, 1-Ring, Proto-Oncogene Proteins c-akt, antagonists & inhibitorsBryostatin 1
go.drugbank.com/drugs/DB11752InvestigationalBryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: Bryostatin 1, Bryostatin-1Tetrahydrocannabivarin
go.drugbank.com/drugs/DB11755InvestigationalCompared to THC which demonstrates its effects through weak partial agonist activity of both endocannabinoid receptors Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R), THCV acts as a CB1 antagonist and a … Further evidence has also shown that THCV acts as an agonist of GPR55 and l-α-lysophosphatidylinositol (LPI) [A32974].
Categories: Serotonin 5-HT1 Receptor AgonistsIstradefylline
go.drugbank.com/drugs/DB11757ApprovedInvestigational[A184067] This region of the brain is highly involved in motor control.[A184067] Istradefylline is indicated as an adjunct treatment to [levodopa] and [carbidopa] for Parkinson's disease. … Istradefylline, or KW6002, was developed by Kyowa Hakko Kirin in Japan for the treatment of Parkinson's disease as an adjunct to standard therapy.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsPF-04991532
go.drugbank.com/drugs/DB11765InvestigationalPF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.
Categories: Heterocyclic Compounds, 1-RingAZD-1305
go.drugbank.com/drugs/DB11766InvestigationalAZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation, and Left Ventricle Function.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates