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Pyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigational[L32408, L32413] In addition to treating myasthenia gravis, pyridostigmine is used to reverse neuromuscular blocks, relieve symptoms in congenital myasthenic syndromes, and protect against certain nerve … By inhibiting the breakdown of acetylcholine in the neuromuscular junction, they increase signalling and relieve symptoms.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: MESTINON TABLET 10 mg, MİYASTU 180 MG UZATILMIŞ SALIMLI TABLET, 30 ADETSolifenacin
go.drugbank.com/drugs/DB01591ApprovedInvestigationalSolifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.
Mixtures: VESOMNİ 6 MG/0.4 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADET, Vesomni 6 mg/0,4 mg Tabletten mit veränderter WirkstofffreisetzungCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesRuxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigationalBy inhibiting JAK1 and JAK2, ruxolitinib works to block the dysregulated cell signalling pathways and prevents abnormal blood cell proliferation. … [A229883] Ruxolitinib has been investigated to treat patients with coronavirus disease 2019 (COVID-19) accompanied by severe systemic hyperinflammation.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: JAKAVİ 10 MG TABLET, 168 ADET, JAKAVİ 10 MG TABLET, 56 ADETTrospium
go.drugbank.com/drugs/DB00209ApprovedInvestigational[L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. … Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: SPASMEX 30 MG FILM TABLET, 100 ADET, SPASMEX 30 MG FILM TABLET, 50 ADETRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets … [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT1 Receptor AntagonistsInternational brands: Risperidal M-TabOmalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigationalBy binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its receptors on immune cells. … [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria, and asthma.[A263507]
Categories: Agents to Treat Airway DiseaseProducts: XOLAIR 150 MG ENJEKSIYONLUK COZELTI İÇİN TOZ İÇEREN FLAKON, 1 ADET, XOLAIR ® 150 MGLormetazepam
go.drugbank.com/drugs/DB13872ApprovedIt is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Synonyms: 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-oneProducts: Sedalor 2 mg/10 ml Injektions-/Infusionslösung, LORETAM 1.0 MGIron protein succinylate
go.drugbank.com/drugs/DB11209ApprovedMixtures: KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK., FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADETProducts: FERPLEX 60 MG ORAL SOLÜSYON, 10 ADET, FERPLEX 40 MG/15 ML ORAL ÇÖZELTİ, 10 ADETMirikizumab
go.drugbank.com/drugs/DB14910ApprovedInvestigationalMirikizumab is a monoclonal antibody developed by Eli Lilly intended to treat ulcerative colitis. … [L46237] In April 2023, the US FDA declined to approve mirikizumab for the treatment of ulcerative colitis on the basis of manufacturing concerns.
Products: Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 2 ADET, Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 6 ADETAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigational[L54773,L54768] As abiraterone has poor oral bioavailability and is susceptible to hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced stability … It is used to treat metastatic castration-resistant prostate cancer, hormone-sensitive high-risk metastatic prostate cancer.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: ABYGA 250 MG TABLET, 120 ADET, ZYTIGA 250 MG TABLET, 120 ADET