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Letrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigationalLetrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. … [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623]
Products: LETROZOLO EG, SOLESTRASA-INVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalinto therapy in the early 1960s. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced
Mixtures: Trandolapril and Verapamil Hydrochloride ER, Trandolapril and Verapamil Hydrochloride ERInternational brands: Verogalid ERLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.
Mixtures: Meds on the Go, Doc in the Box All Day SupplyProducts: LOPERAMIDE EG, IMODIUM NAgalsidase alfa
go.drugbank.com/drugs/DB15874ApprovedInvestigational[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413]
Galcanezumab
go.drugbank.com/drugs/DB14042ApprovedInvestigational[L42060] It is unknown if galcanezumab has an effect on pregnancy outcomes. A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060] … [A33112] Galcanezumab was approved by the FDA in September 2018, and is indicated for the preventive treatment of migraine and the treatment of episodic cluster headache.
Products: EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML, Pontevia 120 mg solution for injection in pre-filled penIndapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigationalorder to achieve blood pressure targets. … [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally.
Mixtures: PERINDOPRIL E INDAPAMIDE EG, PERINDOPRIL E INDAPAMIDE EGMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalAn anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. … the risk of colorectal cancer in conditions like ulcerative colitis is maintained.
Products: MESALAZINA EG, MESALAZINA EG STADAMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigational[T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]
Products: METOPROLOLO EG, Metoprolol Succinate ERCipaglucosidase alfa
go.drugbank.com/drugs/DB16708ApprovedInvestigationalin Pompe disease. … ,[L45275] and the EMA fully approved the drug on March 27, 2023.
Salicylic acid
go.drugbank.com/drugs/DB00936ApprovedInvestigationalVet approvedA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Mixtures: Zaol Doctors Order Scalp Scaling, Zaol Doctors Order Synergy BoosterProducts: Ultrasal-ER, AMINO EX 500mL