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Acitretin
go.drugbank.com/drugs/DB00459ApprovedInvestigationalAn oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Synonyms: (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acidProducts: NOVATRETIN CAPSULE 10MG, Novatretin 10mg CapsulesEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalIt was approved by the U.S. Food and Drug Administration (FDA) in March 2005. … Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Products: BARACLUDE 1MG, ENTECAVIR AL 1MGSorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigationalIt targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor.
Synonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea, 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamideProducts: SORAFENIB EG, NEXAVAR TABLET 200 mgFlunisolide
go.drugbank.com/drugs/DB00180ApprovedIt is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Products: FLUNISOLIDE EGLeuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigational[L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use. … Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced
Products: ELIGARD 22.5 MG ENJ. COZ. ICIN S.C. TOZ ICEREN SIRINGA VE COZUCU ICEREN SIRINGA, 1 ADET, TAPROS 3M DEPOTTerlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigational[A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding.[A252672] The drug was first approved by the FDA in September 2022.[L43217] … Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin.
Products: Glypressin 1mg Injection, GLYPRESSIN 1mg/8.5ml solution for injectionFlubendazole
go.drugbank.com/drugs/DB08974ApprovedInvestigationalWithdrawnFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Products: HELMIN EX SUSPENSION 100MG/5ML, FLUBENDAZOL 300 MGEpinephrine
go.drugbank.com/drugs/DB00668ApprovedInvestigationalVet approvedOn August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353]. … It can be used in severe cases of croup [L4824].
Mixtures: Ana-kit (2mg/tab Orl, 1mg/ml Liq Sc Im), Marcaine ECategories: Sympathomimetics in Glaucoma TherapyCaspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalIt is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc.
Synonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-transProducts: CASPOFUNGIN EG, Nigufo 50 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungBacampicillin
go.drugbank.com/drugs/DB01602ApprovedWithdrawnIt is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. … It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract and acute uncomplicated gonococcal urethritis etc.
Products: BACAMPICILLINA EG, BACAMPICILLINA GET