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Displaying results 611 - 620 of 10000 in total
  1. Drug

    Zoledronic acid

    go.drugbank.com/drugs/DB00399
    ApprovedInvestigational

    [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994.[A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712] … Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid].

    Synonyms: (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid, (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acidSalts: Zoledronate D,L-Lysine Monohydrate
  2. Drug

    Octasulfur

    go.drugbank.com/drugs/DB09353
    Approved

    Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). … After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli.

    Mixtures: Sodium Sulfacetamide and Sulfur Clarifying Wash in a Urea Vehicle, POLY-N OINTMENTProducts: Acne All-Star 3-in-1 Acne Cleanser, Mask and Spot Treatment, Derma E Acne Clarifying Mask
  3. Drug

    Nitroprusside

    go.drugbank.com/drugs/DB00325
    ApprovedInvestigational

    Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency. … Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles).

    Categories: Compounds used in a research, industrial, or household setting, Arteriolar Smooth Muscle, Agents Acting OnProducts: Sodium Nitroprusside In 0.9% Sodium Chloride, N-PRUS
  4. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections. … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.

    Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrroleInternational brands: Tricowas B
  5. Drug

    Fludarabine

    go.drugbank.com/drugs/DB01073
    ApprovedInvestigational

    Fludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.

    Categories: Heterocyclic Compounds, 2-Ring, DNA (Cytosine-5-)-Methyltransferases, antagonists & inhibitorsSynonyms: 2-F-ARAA, 2-fluoro ARA-A
  6. Drug

    Hydrocortisone

    go.drugbank.com/drugs/DB00741
    ApprovedInvestigationalVet approved

    [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. … [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574]

    Synonyms: Kendall's compound F, Reichstein's substance MInternational brands: Polcort H, Preparation H Hydrocortisone Cream
  7. Drug

    Revakinagene taroretcel

    go.drugbank.com/drugs/DB05344
    ApprovedInvestigational

    (rhCNTF) (NTC-201-6A cell line) for surgical intravitreal placement. … [A265115] On March 6, 2025, FDA approved revakinagene taroretcel for the treatment of idiopathic macular telangiectasia type 2.

    Synonyms: An allogeneic human adult retinal pigment epithelial (RPE) cell line stably transfected with a plasmid, Allogeneic human adult retinal pigment epithelial (RPE) cell line stably transfected with a plasmid encoding human ciliary neurotrophic factor (CNTF).
  8. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD. … Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.

    Mixtures: Theophylline 0.8mg/ml In 5% Dextrose Inj, Theophylline in DextroseCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index
  9. Target

    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

    go.drugbank.com/bio_entities/BE0009035
    TargetHumans

    Also specifically interacts with the CoREST corepressor resulting in repression of neuronal specific gene promoters in non-neuronal cells … Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).

    Polypeptides: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
  10. Drug

    Amphotericin B

    go.drugbank.com/drugs/DB00681
    ApprovedInvestigational

    Amphotericin B shows a high order of in vitro activity against many species of fungi. … ranging from 0.03 to 1.0 mcg/mL in vitro.

    Synonyms: AMPH-b, Amfotericina BSalts: Amphotericin B Cholesteryl Sulfate Complex