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Aflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigational[A261130,L47915] Ziv-aflibercept, under the brand name Zaltrap, was developed as an intravenous injection for the treatment of metastatic colorectal cancer, and it was approved by the FDA and EMA in … [L47966,L47971] The intravitreal formulation, under the brand name EYELEA, was approved by the FDA for the treatment of retinopathy of prematurity in preterm infants in February 2023 and for the treatment
Cod liver oil
go.drugbank.com/drugs/DB11321ApprovedNutraceuticalVet approvedAlso being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements. … Cod liver oil is extracted from the liver of cod fish and mainly consists of omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
Mixtures: Wells Brand Cod Liver Oil Softgel CapsulesEtoperidone
go.drugbank.com/drugs/DB09194ApprovedWithdrawnEtoperidone is an atypical antidepressant introduced in Europe in 1977. … It is a phenylpiperazine-substituted triazole derivative with a composition that classifies it as an analog of tradozone and presents a similar pharmacological profile.
Isotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.
Synonyms: 13-RA, cis-RAVenlafaxine
go.drugbank.com/drugs/DB00285ApprovedInvestigationalVenlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). … It was also considered a second-line treatment for obsessive-compulsive disorder (OCD).
Products: VENLAVITAE® 75 MG CÁPSULAS DURAS DE LIBERACIÓN PROLONGADA, VENLAFAXIN 1A 75MG REKClofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Categories: OCT2 Substrates with a Narrow Therapeutic Index, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexSynonyms: Cl-F-Ara-A, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenineElosulfase alfa
go.drugbank.com/drugs/DB09051ApprovedInvestigationalElosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. … Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome.
Peginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigational-2a for the treatment of Hepatitis C [A19593]. … Peginterferon alfa-2a is available as a fixed dose injector (tradename Pegasys) used for the treatment of chronic Hepatitis C.
Synonyms: PEG-IFN alfa-2A, PEG-Interferon alfa-2ACategories: peginterferon alfa-2a, peginterferon alfa-2a, combinationsMecasermin rinfabate
go.drugbank.com/drugs/DB14751ApprovedInvestigationalMecasermin rinfabate manufactured by Insmed Incorporated under the brand name Iplex was approved by the FDA in 2005[L5722]. … In 2007 Insmed withdrew their application for a marketing authorization with The European Medicines Agency[F4075].
Agalsidase alfa
go.drugbank.com/drugs/DB15874ApprovedInvestigational[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta].
Synonyms: alpha-D-galactosidase, alpha-D-galactopyranosidase