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Ramipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalIt is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular
Mixtures: DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADET, DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADETCategories: Agents Acting on the Renin-Angiotensin SystemGefitinib
go.drugbank.com/drugs/DB00317ApprovedInvestigationalActing in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa. … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer.
Synonyms: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamineProducts: GEFITINIB EGTretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceutical[A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. … [A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L.
Mixtures: Dr. Throwers Hydrotet, Dr. Throwers Pbc No. 1Categories: Retinoids for Topical Use in AcneAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Mixtures: Osmolex ER, Osmolex ERProducts: Osmolex ERTrimipramine
go.drugbank.com/drugs/DB00726ApprovedInvestigationalTricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Synonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineProducts: TRIMINEURIN 40 MG/ML Z EIN, Nu-trimipramine Tab 50mgPropafenone
go.drugbank.com/drugs/DB01182ApprovedInvestigationalAn antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Products: PROPAFENONE EG, Nu-propafenoneClarithromycin
go.drugbank.com/drugs/DB01211ApprovedInvestigationalClarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
Products: CLARITROMICINA EG, CLARITROMICINA DR. REDDY'SLevocetirizine
go.drugbank.com/drugs/DB06282ApprovedInvestigational[L7694] Levocetirizine was granted FDA approval in 1995.[L7694]
Mixtures: ANTISS® D, ANTISS® DProducts: LEVOCETIRIZINA EG, DG Health Allergy ReliefRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways … Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain.
Categories: Dopamine D2 Receptor AntagonistsProducts: RISPERIDONE DI RENZO, RISPERIDONE DR. REDDY'SColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L47591] It has also been investigated in other inflammatory and fibrotic conditions.[A183602]
Categories: Preparations With No Effect on Uric Acid MetabolismProducts: PMS-colchicine ER