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Displaying results 6201 - 6210 of 10000 in total
  1. Drug

    GX-19 Vaccine

    go.drugbank.com/drugs/DB15891
    Investigational

    As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488]. … The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758].

  2. Drug

    Bleomycin A6

    go.drugbank.com/drugs/DB12992
    Investigational

    It was shown that besides the antitumor effect, Bleomycin A6 had the ability to alter the tumor microenvironment and could contribute toward lung cancer relapse and metastasis on long-term treatment. … The development of this drug, apparently, was discontinued.

  3. Drug

    AGuIX

    go.drugbank.com/drugs/DB18189
    Investigational

    It is under development as a radiosensitizer to be used during radiation treatment of malignant glioma.

  4. Drug

    Pacmilimab

    go.drugbank.com/drugs/DB18873
    Investigational

    Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).

  5. Drug

    ABT-639

    go.drugbank.com/drugs/DB15055
    Investigational

    ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain).

  6. Drug

    Mibenratide

    go.drugbank.com/drugs/DB15195
    Investigational

    Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic … Receptor Autoantibodies).

  7. Drug

    V-SARS

    go.drugbank.com/drugs/DB15812
    Investigational

    This therapeutic concept was applied to the development of V-SARS, which heat inactivates the plasma, and packages it into a once-daily pill form. … [COVID-19 convalescent plasma] is currently being acquired from recovered COVID-19 patients and used as prophylaxis for the virus.

  8. Drug

    Flizasertib

    go.drugbank.com/drugs/DB21613
    Investigational

    The usage of the INN stem '-sertib' in the name indicates that Flizasertib is a serine/threonine kinase inhibitor. … Flizasertib is under investigation in clinical trial NCT06602453 (A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse

  9. Drug

    NasoVAX

    go.drugbank.com/drugs/DB15859
    Investigational

    The compound has already shown to be tolerated with no adverse effects or fever in healthy individuals with a nearly 6-fold cellular immune response in comparison to an injectable vaccine[L16313].

  10. Drug

    Talopram

    go.drugbank.com/drugs/DB09190
    Experimental

    Talopram is a selective norepinephrine reuptake inhibitor (SNRI) that is structurally similar to citalopram and melitracen. It was researched in the 1960s and 1970s but never marketed.