Search
Pegademase
go.drugbank.com/drugs/DB00061ApprovedWithdrawnBovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended serum half life.
AN0128
go.drugbank.com/drugs/DB05054InvestigationalAN0128 is a novel compound that contains a boron atom within a borinic acid complex. … AN0128 is a good candidate for a topical antibiotic and is currently being developed by Anacor as a novel therapeutic for acne and atopic dermatitis.
Sagopilone
go.drugbank.com/drugs/DB12391InvestigationalIt is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. … Epothilones are 16-member ring macrolides with antimicrotubule activity that share a similar mechanism of action to the taxanes but have demonstrated potent antiproliferative activity in several different
KP-1461
go.drugbank.com/drugs/DB05644InvestigationalDesignated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases. … KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue.
Stanozolol
go.drugbank.com/drugs/DB06718ApprovedVet approvedStanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema.
SRP 299
go.drugbank.com/drugs/DB05440ExperimentalMycobacterium vaccae is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity of regulatory T-cells that surpress inappropriate Th2 … A specific subset of serotonergic neurons in the interfascicular part of the dorsal raphe nucleus (DRI) is believed to be involved, based on studies with mice.
Robenidine
go.drugbank.com/drugs/DB11542ExperimentalVet approvedRobenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. … Robenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant economic burden.
TGAAC94
go.drugbank.com/drugs/DB06175InvestigationaltgAAC94 is a recombinant adeno-associated virus serotype 2 (AAV2) vector containing the cDNA for a human tumor necrosis factor receptor (TNFR)-immunoglobulin (IgG1) Fc fusion (TNFR:Fc) gene. … The Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038]
Epofolate
go.drugbank.com/drugs/DB12266InvestigationalEpofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells. … tolerable and toxicities known to be associated with epothilone class of anticancer agents were common, although peripheral neuropathy and neutropenia appear to have been less frequent and less severe as