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MK-2748
go.drugbank.com/drugs/DB15371InvestigationalMK-2748 is under investigation in clinical trial NCT01593735 (A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)).
Tilmanocept
go.drugbank.com/drugs/DB15373ApprovedInvestigationalWithdrawnTilmanocept is under investigation in clinical trial NCT03241446 (Pharmacokinetics and Dosimetry of Tc 99m Tilmanocept Following a Single Intravenous Dose Administration in Male and Female Subjects Diagnosed
Clomethiazole
go.drugbank.com/drugs/DB06470InvestigationalIt is also used for the management of agitation, restlessness, short-term insomnia and Parkinson's disease in the elderly. … It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingCiticoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. … It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Categories: Heterocyclic Compounds, 1-RingSynonyms: citidin difosfato de colina, Cytidine 5'-diphosphocholineCOCAINE ESTERASE (RBP-8000)
go.drugbank.com/drugs/DB19225InvestigationalRBP-8000 is under investigation in clinical trials (A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse) for the treatment of Cocaine
Synonyms: COCAINE ESTERASE T172R/G173Q MUTANT (RHODOCOCCUS SP. (STRAIN MB1 BRESLER)Ditazole
go.drugbank.com/drugs/DB08994ApprovedWithdrawnDitazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone. … Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade name Ageroplas.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,2'-(4,5-Diphenyloxazol-2-ylazanediyl)diethanolSR-9009
go.drugbank.com/drugs/DB14013ExperimentalSR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues … SR-9009 is a REV-ERB agonist.
Synonyms: 1-Pyrrolidinecarboxylic acid, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-, ethyl esterCategories: Heterocyclic Compounds, 1-RingMF-300
go.drugbank.com/drugs/DB32060InvestigationalAs a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983] … MF-300 is an investigational, first-in-class, small molecule inhibitor of 15-hydroxyprostaglandin dehydrogenase.
Ninerafaxstat
go.drugbank.com/drugs/DB21486InvestigationalNinerafaxstat is under investigation in clinical trial NCT07023614 (A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy … Ninerafaxstat is a small molecule drug.