Search
CLX-0921
go.drugbank.com/drugs/DB05854ExperimentalIt is a pharmacologically active antihyperglycemic agent that acts by increasing peripheral tissue sensitivity to insulin. … This substance targets the protein peroxisome proliferator-activated receptor gamma.
Categories: Heterocyclic Compounds, 1-RingCOCAINE ESTERASE (RBP-8000)
go.drugbank.com/drugs/DB19225InvestigationalRBP-8000 is under investigation in clinical trials (A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse) for the treatment of Cocaine
Synonyms: COCAINE ESTERASE T172R/G173Q MUTANT (RHODOCOCCUS SP. (STRAIN MB1 BRESLER)Citicoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. … It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Synonyms: citidin difosfato de colina, Cytidine 5'-diphosphocholineCategories: Heterocyclic Compounds, 1-RingDitazole
go.drugbank.com/drugs/DB08994ApprovedWithdrawnDitazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone. … Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade name Ageroplas.
Synonyms: 2,2'-(4,5-Diphenyloxazol-2-ylazanediyl)diethanolCategories: Heterocyclic Compounds, 1-RingDeoxyribonuclease I
go.drugbank.com/drugs/DB16523InvestigationalDeoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7[A227723]. It is normally found in saliva, urine, pancreatic secretions, and blood[A227723]. … Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum, and recurrent exacerbations of respiratory
Synonyms: DNase I, Deoxyribonuclease ICategories: Deoxyribonuclease I, antagonists & inhibitorsInositol 1,3-bisphosphate
go.drugbank.com/drugs/DB02942ExperimentalThe compound corresponds to the soluble headgroup of phosphatidylinositol 3-phosphate (PtdIns(3)P), an endosomal signaling lipid recognized by FYVE domains, and it has been used as a ligand in structural … Inositol 1,3-bisphosphate is a phosphorylated myo-inositol derivative and small molecule metabolite in which phosphate groups occupy the 1 and 3 positions of the inositol ring.
Nitenpyram
go.drugbank.com/drugs/DB11438ExperimentalVet approvedIt is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly in the central nervous system of insects, causing rapid death. … Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets.
Synonyms: (E)-nitenpyram, (1E)-N-((6-chloro-3-pyridinyl)methyl)-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamineCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingNitrocefin
go.drugbank.com/drugs/DB11592ExperimentalNitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. … While other detection methods exist, such as PCR, nitrocefin allows for rapid detection using few materials and inexpensive equipment.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingSR-9011
go.drugbank.com/drugs/DB14014ExperimentalSR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues … SR-9011 is a REV-ERB agonist.
Synonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-Categories: Heterocyclic Compounds, 1-RingRacivir
go.drugbank.com/drugs/DB12753InvestigationalRacivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. … Racivir is a 50:50 mixture of [emtricitabine] and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections.
Categories: Heterocyclic Compounds, 1-Ring