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AER001
go.drugbank.com/drugs/DB05078InvestigationalAER001, an IL4/13 receptor antagonist for severe asthma and eczema currently in Phase 2 studies.
Bithionol
go.drugbank.com/drugs/DB04813ApprovedWithdrawnBithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. … Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32 FR 15046)).
Categories: Antiparasitic Products, Insecticides and RepellentsCardarine
go.drugbank.com/drugs/DB05416InvestigationalCardarine has been investigated for the treatment of Obesity, Lipid Disorders, and Cardiovascular Disease. … Cardarine (GW-501516) is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia.
Denibulin
go.drugbank.com/drugs/DB05932ExperimentalDenibulin is a novel small molecule Vascular Disrupting Agent under development by MediciNova for treatment of solid tumor cancers.
Dihydroxymethoxychalcone
go.drugbank.com/drugs/DB14122InvestigationalCardamonin's name comes from the fact that it can be found in cardamom spice. … Cardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits
N4-Hydroxycytidine
go.drugbank.com/drugs/DB15660Experimental[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. … [A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses in mice and human airway epithelial cells.
Synonyms: 4-N-Hydroxycytidine, N(4)-HydroxycytidineCategories: Nucleic Acids, Nucleotides, and NucleosidesFosinoprilat
go.drugbank.com/drugs/DB14207ExperimentalFosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Categories: Amino Acids, Peptides, and Proteins, Agents Acting on the Renin-Angiotensin SystemCalcimycin
go.drugbank.com/drugs/DB19408InvestigationalCalcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis. … It binds to and transports calcium and other divalent cations across membranes, disrupts oxidative phosphorylation, and inhibits ATPase in rat liver mitochondria.
Categories: Benzoxazoles and derivatives, Compounds used in a research, industrial, or household settingTrestolone acetate
go.drugbank.com/drugs/DB13958ExperimentalIt is an androgen ester – specifically, the C17 acetate ester of [DB05830]. … Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed.
Categories: Testosterone and derivatives, Hormones, Hormone Substitutes, and Hormone AntagonistsSynonyms: 17β-Hydroxy-7α-methylestr-4-en-3-one acetate, 17beta-Hydroxy-7alpha-methylestr-4-en-3-one acetatePsilocybin
go.drugbank.com/drugs/DB11664InvestigationalPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.