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Aficamten
go.drugbank.com/drugs/DB18490ApprovedInvestigationalAficamten is a cardiac myosin inhibitor. Approved by the FDA on December 19, 2025, aficamten is indicated for the treatment of adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) to improve functional capacity and symp...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesBorage oil
go.drugbank.com/drugs/DB11238ApprovedBorage oil is used as an herbal treatment of skin disorders including eczema, seborrheic dermatitis, and neurodermatitis as well as other inflammatory, cardiovascular and endocrine disorders, although
Carbazochrome
go.drugbank.com/drugs/DB09012ApprovedWithdrawnIt is an oxidation product of adrenaline which enhances the microcirculatory tone [A19747].
International brands: Di Ka Ning, Le Ka NingCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsTedizolid phosphate
go.drugbank.com/drugs/DB09042ApprovedThis product is currently available as both an oral tablet and as a powder for intravenous injection.[L11232]
TC-2216
go.drugbank.com/drugs/DB06044InvestigationalTC-2216 is an investigational novel small molecule that is being developed as an oral treatment for depression and anxiety disorders.
Laquinimod
go.drugbank.com/drugs/DB06685InvestigationalLaquinimod is an immunomodulator developed by Active Biotech and produced by Teva Pharmaceutical Industries. … It is currently under development in phase III trials for treatment of multiple sclerosis as an oral therapy, like fingolimod.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesRecombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741Investigational._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels.
Vabametkib
go.drugbank.com/drugs/DB21629InvestigationalVabametkib has a monoisotopic molecular weight of 566.3 Da.
Ligandrol
go.drugbank.com/drugs/DB13934InvestigationalLigandrol is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting and osteoporosis.
MaaT013
go.drugbank.com/drugs/DB18648InvestigationalMaaT013 is an allogeneic fecal microbiota therapy. It is being investigated for the treatment of Graft-Versus-Host Disease.