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Displaying results 6331 - 6340 of 10000 in total
  1. Drug

    NGN-401

    go.drugbank.com/drugs/DB18594
    Investigational

    protein 2 (MECP2). … NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding

    Synonyms: Recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2
  2. Target

    3-oxo-5-alpha-steroid 4-dehydrogenase 2

    go.drugbank.com/bio_entities/BE0000585
    TargetEnzymeHumans

    Catalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed

    Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2Synonyms: S5AR 2, SR type 2
  3. Target

    Actin-related protein 2/3 complex subunit 4

    go.drugbank.com/bio_entities/BE0004254
    TargetHumans

    The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). … Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079).

    Polypeptides: Actin-related protein 2/3 complex subunit 4Synonyms: Arp2/3 complex 20 kDa subunit
  4. Drug

    Nadolol

    go.drugbank.com/drugs/DB01203
    ApprovedInvestigational

    Nadolol is a nonselective beta adrenal receptor blocker that is used to lower blood pressure.

    Mixtures: CORGARETIC (NADOLOL/ BENDROFLUMETIAZIDA) 80/5 MG, Corzide Tab W Nadolol 80mgCategories: MATE 2 Substrates, MATE 1 Substrates
  5. Drug

    Olopatadine

    go.drugbank.com/drugs/DB00768
    Approved

    It is a structural analog of [doxepin], which has a minimal anti-allergic activity. … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions.

    Mixtures: OFNOL FRESH % 0.1 + %0.15 STERİL OFTALMİK ÇÖZELTİ, 1 ADETCategories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 Substrates
  6. Drug

    Piperazine

    go.drugbank.com/drugs/DB00592
    ApprovedVet approvedWithdrawn

    Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. … Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: MEI-MEI WORM SYRUP 750 mg/5 ml, PIPOL® JARABE
  7. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Still docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].

    Mixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, Senna Plus Standardized Senna Concentrate 8.6 mg and Docusate Sodium 50 mg EachProducts: M-docusate Sodium 100 mg, M-docusate Calcium
  8. Drug

    Meclizine

    go.drugbank.com/drugs/DB00737
    ApprovedInvestigational

    Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties.

    Mixtures: VELOXIN TABLET 25/50mgCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  9. Drug

    Gadoversetamide

    go.drugbank.com/drugs/DB00538
    Approved

    Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.

    Categories: Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINA 100 MG / 10 ML, OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZELTI ICEREN KUL.HAZIR SIRINGA, 30 ML
  10. Drug

    Agalsidase beta

    go.drugbank.com/drugs/DB00103
    ApprovedInvestigational

    Agalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.

    Products: REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, FABRAZYME 35 MG İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE TOZ, 1 ADET