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Homocysteine
go.drugbank.com/drugs/DB04422InvestigationalHomocysteine is a thiol-containing amino acid formed by a demethylation of methionine.
Categories: Amino Acids, Peptides, and ProteinsMeplazumab
go.drugbank.com/drugs/DB16465InvestigationalMeplazumab is a humanized anti-CD147 antibody being investigated as an add-on therapy in patients with COVID-19 pneumonia.
Categories: Amino Acids, Peptides, and ProteinsTozorakimab
go.drugbank.com/drugs/DB16473InvestigationalTozorakimab (MEDI3506), developed by AstraZeneca, was investigated in multiple clinical trials to evaluate its safety, tolerability, efficacy, and pharmacokinetics across various conditions. … These trials include NCT03096795 (completed; healthy participants, COPD patients, and healthy Japanese participants), NCT05070312 (completed; healthy Chinese participants), NCT04212169 (completed with
Cergutuzumab amunaleukin
go.drugbank.com/drugs/DB14874InvestigationalCergutuzumab amunaleukin is under investigation in clinical trial NCT02004106 (A Study to Evaluate Safety, Pharmacokinetics, and Efficacy of RO6895882 in Participants With Advanced and/or Metastatic Solid
Categories: Amino Acids, Peptides, and ProteinsPamrevlumab
go.drugbank.com/drugs/DB14952InvestigationalPamrevlumab is under investigation in clinical trial NCT00913393 (Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapy).
Categories: Amino Acids, Peptides, and ProteinsSCB-2019
go.drugbank.com/drugs/DB15805InvestigationalThis vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture. The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. … As of June 2020, the company is pursuing a randomized, double blind, placebo controlled study (NCT04405908) to test the safety and immunogenicity of the vaccine.
Mocetinostat
go.drugbank.com/drugs/DB11830InvestigationalMocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.
AZD-7268
go.drugbank.com/drugs/DB19203InvestigationalAZD-7268 is under investigation in clinical trial NCT01020799 (AZD7268 Safety and Tolerability Study).
OM85
go.drugbank.com/drugs/DB16533InvestigationalOM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
Propidium
go.drugbank.com/drugs/DB02166ExperimentalQuaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes
Categories: Indicators and Reagents