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Displaying results 6341 - 6350 of 10000 in total
  1. Drug

    Norflurane

    go.drugbank.com/drugs/DB13116
    ApprovedInvestigationalWithdrawn

    Norflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).

  2. Drug

    TH0318

    go.drugbank.com/drugs/DB05145
    Experimental

    TH0318 is a stabilized analogue of human GLP-1 (glucagon-like peptide-1) under investigation for the treatment of type 2 diabetes.

  3. Drug

    ADL 10-0101

    go.drugbank.com/drugs/DB05443
    Experimental

    ADL 10-0101 is a peripheral kappa opioid agonist analgesic product candidate. … Because ADL 10-0101 does not cross the blood-brain barrier and enter the brain when administered at therapeutic doses, it is expected to avoid central nervous system side effects.

  4. Drug

    Hyaluronidase (ovine)

    go.drugbank.com/drugs/DB00070
    Approved

    Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.

  5. Drug

    MAS825

    go.drugbank.com/drugs/DB16452
    Investigational

  6. Drug

    Rasburicase

    go.drugbank.com/drugs/DB00049
    ApprovedInvestigational

    Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified <i>Saccharomyces cerevisiae</i> strain.

  7. Drug

    Enpatoran

    go.drugbank.com/drugs/DB16501
    Investigational

    It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327). … Enpatoran (M5049) was under investigation in clinical trials for various conditions.

  8. Drug

    Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen

    go.drugbank.com/drugs/DB16711
    ApprovedInvestigational

    It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection. … The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein carrier CRM197 to form the glycoconjugate.

  9. Drug

    Pregnenolone

    go.drugbank.com/drugs/DB02789
    ApprovedInvestigationalWithdrawn

    A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.

  10. Drug

    Ciglitazone

    go.drugbank.com/drugs/DB09201
    Experimental

    Ciglitazone significantly decreases VEGF production by human granulosa cells in an in vitro study, and may potentially be used in ovarian hyperstimulation syndrome. … Ciglitazone is a potent and selective PPARγ ligand with an EC50 of 3.0 µM. It is also an anti-hyperglycemic agent in the ob/ob murine model in vivo.