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Displaying results 631 - 640 of 1993 in total
  1. Target

    Thyroid hormone receptor

    go.drugbank.com/bio_entities/BE0009811
    TargetHumans and other mammals

    Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine … Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine

    Polypeptides: Thyroid hormone receptor alpha, Thyroid hormone receptor betaSynonyms: Nuclear receptor subfamily 1 group A member 1, Nuclear receptor subfamily 1 group A member 2
  2. Target

    Olfactory receptor 1D2

    go.drugbank.com/bio_entities/BE0013079
    TargetHumans

    Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro.

    Polypeptides: Olfactory receptor 1D2Synonyms: Olfactory receptor 17-4, Olfactory receptor OR17-6
  3. Target

    Relaxin receptor 2

    go.drugbank.com/bio_entities/BE0017729
    TargetHumans

    Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. … May also be a receptor for Leydig insulin-like peptide (INSL3)

    Polypeptides: Relaxin receptor 2Synonyms: Leucine-rich repeat-containing G protein-coupled receptor 8, G protein-coupled receptor 106
  4. Drug

    Tivantinib

    go.drugbank.com/drugs/DB12200
    Investigational

    Tivantinib has been investigated in Solid Tumors.

    Categories: Proto-Oncogene Proteins c-met, antagonists & inhibitors
  5. Drug

    Levomilnacipran

    go.drugbank.com/drugs/DB08918
    ApprovedInvestigational

    Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. Levomilnacipran is the more active 1S,2R-enantiomer in the ...

  6. Drug

    Lucanthone

    go.drugbank.com/drugs/DB04967
    Investigational

    (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.

  7. Drug

    Iron sucrose

    go.drugbank.com/drugs/DB09146
    ApprovedInvestigational

    Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) an...

  8. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiti...

    Products: Med-rosuvastatin
  9. Drug

    Sodium phosphate, monobasic, unspecified form

    go.drugbank.com/drugs/DB14503
    Approved

    Mixtures: Uta, Uta
  10. Target

    Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

    go.drugbank.com/bio_entities/BE0018277
    TargetHumans

    Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:

    Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A