Search
Sulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigational[A255592] Meta-analysis of 19 randomized controlled trials indicated that sulfasalazine is superior to placebo in inducing remission; however, with no supported evidence of mucosal healing, sulfasalazine
Synonyms: 5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid, 5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acidFluoride ion F-18
go.drugbank.com/drugs/DB09398ApprovedInvestigationalNo adverse reactions have been reported. … Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added.
Meradimate
go.drugbank.com/drugs/DB11096ApprovedMeradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved ...
Mixtures: Body Armor Sun 'n Bug BlockMetronidazole
go.drugbank.com/drugs/DB00916ApprovedInvestigationalMetronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic inf...
Mixtures: PERFESSIL NF, METARSAL N CAPSULASCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesFruquintinib
go.drugbank.com/drugs/DB11679ApprovedInvestigationalFruquintinib is a novel small-molecule anti-VEGFR that targets VEGFR-1,-2, and -3 to inhibit angiogenesis. Tumor angiogenesis is one of the most critical biological processes for increasing oxygen and nutrient supply to cancer cells, and...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesNKG2D-ACE2 CAR-NK Cell
go.drugbank.com/drugs/DB15727InvestigationalThe transmembrane NKG2D and intracellular 2B4 domains are required for optimal NK signalling and subsequent cell-mediated cytotoxicity. … These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF.
Synonyms: ACE2 CAR-NK Cell, NKG2D CAR-NK CellN-methylnicotinamide
go.drugbank.com/drugs/DB08840InvestigationalN-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine
Synonyms: N-Methyl nicotineamide, 3-(N-Methylcarbamoyl)pyridineLenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigationalLenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomi...
Categories: P-glycoprotein substratesBismuth subnitrate
go.drugbank.com/drugs/DB13209ApprovedWithdrawnBismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate...