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Displaying results 631 - 640 of 10000 in total
  1. Drug

    Adapalene

    go.drugbank.com/drugs/DB00210
    ApprovedInvestigational

    Differin was later made available as 0.1% gel, cream, or lotion, or 0.3% gel products. On December 8th, 2008, Galderma Labs gained FDA approval for Epiduo®, a 0.1% adapalene, 2.5% BPO combination gel. … Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris.[A193518] Adapalene has similar efficacy but a superior safety profile compared to tretinoin.

    Categories: Anti-Acne Preparations for Topical Use, Retinoids for Topical Use in Acne
  2. Drug

    Picosulfuric acid

    go.drugbank.com/drugs/DB09268
    ApprovedInvestigational

    Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. … The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in European countries for many years.[A33322]

    Mixtures: AGAROL CON SABOR A FRAMBUESA, PICOPREP Powder for Oral SolutionCategories: Drugs for Constipation
  3. Drug

    Andexanet alfa

    go.drugbank.com/drugs/DB14562
    Approved

    However, the use of these agents is associated with a risk for uncontrollable bleeding episodes that can lead to can cause serious or fatal bleeding. … Andexanet alfa retains the structural similarity to that of endogenous human factor Xa, but exists in its mature functional form without the need for activation via the intrinsic or extrinsic coagulation

  4. Drug

    Manganese gluconate

    go.drugbank.com/drugs/DB11141
    Approved

    Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement. … Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O.

    Mixtures: Pro Enz Tab, Multi-force for Women Tab
  5. Drug

    Melphalan

    go.drugbank.com/drugs/DB01042
    ApprovedInvestigational

    Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. … [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.

    Mixtures: Melphalan for Injection, Melphalan for InjectionSynonyms: L-PAM, L-Sarcolysin
  6. Drug

    Acetyldigitoxin

    go.drugbank.com/drugs/DB00511
    Approved

    Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Desglucolanatoside A
  7. Drug

    Nevirapine

    go.drugbank.com/drugs/DB00238
    ApprovedInvestigational

    A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS.

    Mixtures: Zidovex LN (Lamivudine 150mg, Zidovudine 300mg, Nevirapine 200mg Tablets)Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Uridine triacetate

    go.drugbank.com/drugs/DB09144
    Approved

    As a result of UMPS deficiency, patients experience a systemic deficiency of pyrimidine nucleotides, accounting for most symptoms of the disease. … By pre-administering with uridine (as the prodrug uridine triacetate), higher doses of 5-FU can be given allowing for improved efficacy and a reduction in toxic side effects [A18578].

  9. Drug

    Elbasvir

    go.drugbank.com/drugs/DB11574
    Approved

    in the NS5A protein and previous treatment failure with [ribavirin], [peginterferon alfa-2a], [peginterferon alfa-2b], or other NS3/4A inhibitors like [boceprevir], [simeprevir], or [telaprevir]. … [L10253] Elbasvir and [grazoprevir] are used with or without [ribavirin] with the intent to cure, or achieve a sustained virologic response (SVR), and have been shown to achieve a SVR between 94% and 97%

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  10. Drug

    Chromic chloride

    go.drugbank.com/drugs/DB09129
    Approved

    Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).

    Mixtures: One-A-day Advance Men's, Addaven Concentrate for Solution for InfusionCategories: Compounds used in a research, industrial, or household setting