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Displaying results 6391 - 6400 of 10000 in total
  1. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders.

    Mixtures: ORAZOLE ® 10 MG CAPSULA, OMEPRAZOL 20 MGCategories: 2-Pyridinylmethylsulfinylbenzimidazoles, Heterocyclic Compounds, 2-Ring
  2. Drug

    Dydrogesterone

    go.drugbank.com/drugs/DB00378
    ApprovedInvestigationalWithdrawn

    A synthetic progestational hormone with no androgenic or estrogenic properties.

    Mixtures: Femoston conti 1 mg/5 mg Filmtabletten, FEMOSTON 2/10MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Enfuvirtide

    go.drugbank.com/drugs/DB00109
    ApprovedInvestigational

    Enfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake … The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesProducts: FUZEON POLVO SOLUCION INYECTABLE 90 MG/MI
  4. Drug

    Nebivolol

    go.drugbank.com/drugs/DB04861
    ApprovedInvestigational

    Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. … [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol].

    Mixtures: VASDAY 5 MG/5 MG/25 MG FİLM KAPLI TABLET (30 ADET), AMLONEB 5 MG/5 MG TABLET, 30 ADETCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 Substrates
  5. Drug

    Nalotimagene carmaleucel

    go.drugbank.com/drugs/DB19155
    Investigational

    Synonyms: Cells are derived from the haematopoietic stem cell (HSC) donor and are genetically modified ex vivo with a non-replicative SFCMM-3 gamma- retroviral vector derived from Mo, human culture expanded activated allogeneic T cells for adjunctive immunotherapy.
  6. Drug

    Vancomycin

    go.drugbank.com/drugs/DB00512
    ApprovedInvestigational

    It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. … As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and enterocolitis

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: VANEOTIK® 125 MG, VANEOTIK® 250 MG CAPSULAS
  7. Drug

    Nadroparin

    go.drugbank.com/drugs/DB08813
    ApprovedInvestigationalWithdrawn

    It is derived from porcine sources and has a mean molecular size of 5000 daltons. … Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa.

    Mixtures: FRAXIPARINE 0.3 MLProducts: FRAXODI 19000 IU AXA/1 ML SC ENJEKTABL SOLUSYON 2 ENJEKTOR, FRAXIPARINE 2850 IU/0.3 ML 2 ENJEKTOR
  8. Drug

    Marstacimab

    go.drugbank.com/drugs/DB17725
    ApprovedInvestigational

    Marstacimab is a human monoclonal immunoglobulin G Type 1 (IgG1) antibody produced by Chinese hamster ovary (CHO) cells by recombinant DNA technology. … [L51803] It is a tissue factor pathway inhibitor (TFPI) antagonist, which is an endogenous anticoagulant.

    Synonyms: Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1-chain), disulfide with human monoclonal pf-06741086 .lambda.-chain, dimerProducts: Hympavzi 150 mg/mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)
  9. Drug

    Spironolactone

    go.drugbank.com/drugs/DB00421
    ApprovedInvestigational

    Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. … [A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243]

    Mixtures: Clindamycin 1% / Niacinamide 4% / Spironolactone 2% / Tretinoin 0.025%, Niacinamide 4% / Spironolactone 5%Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 Inhibitors
  10. Drug

    Bivalirudin

    go.drugbank.com/drugs/DB00006
    ApprovedInvestigational

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.

    Products: OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 1 ADET, BIVACARD 250 MG IV ENJEKSIYON VE INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET