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Displaying results 6391 - 6400 of 10000 in total
  1. Drug

    Guretolimod

    go.drugbank.com/drugs/DB21487
    Investigational

    Guretolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Guretolimod is a toll-like receptor (TLR) agonist. … Guretolimod is under investigation in clinical trial NCT03416335 (A Study of DSP-0509 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile).

  2. Drug

    Ocedurenone

    go.drugbank.com/drugs/DB21519
    Investigational

    Ocedurenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist. … Ocedurenone is under investigation in clinical trial NCT04968184 (Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe Chronic Kidney Disease (CKD)).

  3. Drug

    Selnoflast

    go.drugbank.com/drugs/DB21522
    Investigational

    Selnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor. … Selnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic

  4. Drug

    Brimarafenib

    go.drugbank.com/drugs/DB21706
    Investigational

    Brimarafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. … Brimarafenib is under investigation in clinical trial NCT04249843 (Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants with Advanced or Refractory Tumors).

  5. Drug

    Padoprazan

    go.drugbank.com/drugs/DB21689
    Experimental

    Padoprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Padoprazan is a proton pump inhibitor, not dependent on acid activation. … Padoprazan has a monoisotopic molecular weight of 405.12 Da.

  6. Drug

    TAK-751S

    go.drugbank.com/drugs/DB06432
    Investigational

    TAK-751S is a synthetic analog of Shiga toxin (Stx) receptor, Gb3, produced by enterohemorrhagic _Escherichia coli_.[A260296]

  7. Drug

    CA-170

    go.drugbank.com/drugs/DB15772
    Investigational

    CA-170 is a selective, small molecule inhibitor of PD-L1.

  8. Drug

    rPSGL-Ig

    go.drugbank.com/drugs/DB06256
    Investigational

    Recombinant P-selectin glycoprotein ligand IgG fusion protein (rPSGL-Ig) is a fusion protein of human P-selectin ligand and IgG1-Fc.

    Synonyms: rPSGL-Ig, rPSGL-1-Ig
  9. Drug

    Osanetant

    go.drugbank.com/drugs/DB04872
    Investigational

    In a review of its R&D portfolio, the company announced in August 2005 that it would cease any further development of osanetant. … Developed by Sanofi-Aventis (formerly Sanofi-Synthelabo), osanetant (SR-142801) is an NK3 receptor antagonist which was under development for the treatment of schizophrenia and other Central Nervous System

  10. Drug

    Onametostat

    go.drugbank.com/drugs/DB21480
    Investigational

    Onametostat is a small molecule drug. The usage of the INN stem '-metostat' in the name indicates that Onametostat is a histone N-methyltransferase inhibitor. … Onametostat is under investigation in clinical trial NCT06788509 (A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring).