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Displaying results 6401 - 6410 of 10000 in total
  1. Drug

    Insulin efsitora alfa

    go.drugbank.com/drugs/DB19013
    Investigational

    Basal Insulin for the First Time (QWINT-1)). … Insulin efsitora alfa is under investigation in clinical trial NCT05662332 (A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting

  2. Drug

    Zosurabalpin

    go.drugbank.com/drugs/DB21539
    Investigational

    Zosurabalpin is under investigation in clinical trial NCT05614895 (A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections).

  3. Drug

    FX06

    go.drugbank.com/drugs/DB05685
    Investigational

    FX06 is a naturally occurring peptide derived from the neo-N-terminus of fibrin (Bbeta(15-42)). It prevents leukocyte migration through the gap junctions of endothelial cells.

  4. Drug

    MVA-SARS-2-S

    go.drugbank.com/drugs/DB16432
    Investigational

    MVA is a highly attenuated poxvirus vector[A226603] that has a high-level of biological safety due to its quality of being a non-replicating virus in mammalian hosts[L30458] and is used to develop vaccines … MVA-SARS-2-S is a COVID-19 vaccine candidate that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein[L30453].

  5. Drug

    CYC116

    go.drugbank.com/drugs/DB05198
    Investigational

    Cyclacel's small molecule investigational drug, CYC116, is the third orally-available Cyclacel drug to enter development, which demonstrated anticancer activity with a mechanism consistent with inhibition

  6. Drug

    Methopterin

    go.drugbank.com/drugs/DB16620
    Investigational

    Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.[A229843]

  7. Drug

    Valinomycin

    go.drugbank.com/drugs/DB14057
    Experimental

    A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. … It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring.

  8. Drug

    XmAb 2513

    go.drugbank.com/drugs/DB06324
    Investigational

    XmAb 2513 is a humanized monoclonal antibody that targets the antigen CD30, a molecule expressed on the surface of a number of tumor cell types. … It has been investigated for the treatment of hodgkin’s lymphoma.

  9. Drug

    Deferitazole

    go.drugbank.com/drugs/DB13120
    Investigational

    It has been used in trials studying the treatment and basic science of Beta-thalassemia, Hepatic Impairment, Impaired Renal Function, Transfusional Iron Overload, and Iron Overload Due to Repeated Red

  10. Drug

    POT-4

    go.drugbank.com/drugs/DB06056
    Investigational

    POT-4 is a peptide that specifically inhibits complement activation and is initially being developed for the treatment of age-related macular degeneration (AMD). … The investigational drug was under investigation in clinical trial NCT00473928 (Safety of Intravitreal POT-4 Therapy for Patients With Neovascular Age-Related Macular Degeneration (AMD) (ASaP)).