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Displaying results 6451 - 6460 of 10000 in total
  1. Drug

    Lenabasum

    go.drugbank.com/drugs/DB12193
    Investigational

    Ajulemic acid has been used in trials studying the treatment of Cystic Fibrosis, Dermatomyositis, and Diffuse Cutaneous Systemic Sclerosis.

    Categories: Cannabinoids and similars, Hormones, Hormone Substitutes, and Hormone Antagonists
  2. Drug

    SAR445136

    go.drugbank.com/drugs/DB17708
    Investigational

    SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy. … [A259063] It was formerly investigated for the treatment of beta-thalassemia, and it is currently being investigated for the treatment of sickle cell disease.[L46148]

  3. Drug

    Brecanavir

    go.drugbank.com/drugs/DB04887
    Investigational

    Brecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV.

  4. Drug

    Mosapride

    go.drugbank.com/drugs/DB11675
    Investigational

    Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). … Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.

    Categories: Alimentary Tract and Metabolism
  5. Drug

    Zorifertinib

    go.drugbank.com/drugs/DB14795
    Investigational

    AZD-3759 is under investigation in clinical trial NCT03360929 (Evaluate Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of AZD3759).

  6. Target

    Eph receptors

    go.drugbank.com/bio_entities/BE0028186
    TargetHumans

    EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. … Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt

    Synonyms: EPH- and ELK-related kinase
  7. Drug

    TRV-120027

    go.drugbank.com/drugs/DB12199
    Investigational

    TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease.

    Categories: Amino Acids, Peptides, and Proteins
  8. Drug

    Pegdinetanib

    go.drugbank.com/drugs/DB05931
    Investigational

    CT-322 is a proprietary Adnectin(TM) protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis pathway. As a result, CT...

    Categories: Amino Acids, Peptides, and Proteins
  9. Drug

    ARC183

    go.drugbank.com/drugs/DB05124
    Experimental

    The key advantage of ARC183 compared to other thrombin inhibitors is its rapid onset of action and short half-life, giving it the potential to be an ideal agent for medical procedures that require rapid … is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity and

  10. Drug

    Cadmium

    go.drugbank.com/drugs/DB14085
    Experimental

    An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.