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Levophencynonate
go.drugbank.com/drugs/DB16011InvestigationalLevophencynonate is under investigation in clinical trial NCT02299804 (A Clinical Trial to Evaluate Efficacy and Safety of Levophencynonate Hydrochloride in Patient With Vertigo).
Imsidolimab
go.drugbank.com/drugs/DB16658InvestigationalImsidolimab is under investigation in clinical trial NCT03633396 (A Study to Evaluate the Efficacy and Safety of ANB019 in Subjects With Palmoplantar Pustulosis).
PBGM01
go.drugbank.com/drugs/DB18581InvestigationalPBGM01 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, which contains human GLB1 transgene encoding the galactosidase beta 1 enzyme.
Gotistobart
go.drugbank.com/drugs/DB19100InvestigationalGotistobart is under investigation in clinical trial NCT05671510 (ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors).
Pudexacianinium
go.drugbank.com/drugs/DB19161InvestigationalPudexacianinium is under investigation in clinical trial NCT05754333 (A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery).
Synonyms: 3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-2-((1E)-2-((3E)-3-((2E)-2-(3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-1,1-DIMETHYL-1,3-DIHYDRO-2H-BENZO(E)INDOL-2-YLIDENE, -cyclodextrin, 2a-o-(3-aminopropyl)-, diamide with 3-(2-carboxyethyl)-2-(2-(3-(2-(3-(2-carboxyethyl)-1,3-dihydro-1,1-dimethyl-2h-benz(e)indol-2-ylidiene)ethylidene)-2-methoxy-1-cyclohexen-1-yl)ethyleneATR-04
go.drugbank.com/drugs/DB26782InvestigationalATR-04 is under investigation in clinical trial NCT04731259 (Study to Evaluate the Safety of ATR-04).
Metrifonate
go.drugbank.com/drugs/DB11473ExperimentalVet approvedIt is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Etiracetam
go.drugbank.com/drugs/DB11868ExperimentalEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
ReN001
go.drugbank.com/drugs/DB05236InvestigationalReN001 a strong candidate for one of the first cell-based IND applications to be submitted to the Food and Drug Administration in the United States for consideration for the treatment of stroke in humans
V591
go.drugbank.com/drugs/DB16438InvestigationalThrough Merck’s acquisition of Thermis in May 2020, they were able to leverage Thermis’ platform knowledge and accelerate the development of V591 to phase I clinical trials (NCT04498247)[L30593].