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Displaying results 6471 - 6480 of 10000 in total
  1. Drug

    Pentosan polysulfate

    go.drugbank.com/drugs/DB00686
    ApprovedInvestigational

    Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.

  2. Drug

    Atrazine

    go.drugbank.com/drugs/DB07392
    Experimental

    Atrazine is a selective triazine herbicide. Inhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    3'-phospho-5'-adenylyl sulfate

    go.drugbank.com/drugs/DB02902
    Experimental

    It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms. … 3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate

  4. Drug

    Nitrilotriacetic acid

    go.drugbank.com/drugs/DB03040
    Experimental

    Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    RR001

    go.drugbank.com/drugs/DB17369
    Investigational

    RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand

  6. Drug

    RGX-181

    go.drugbank.com/drugs/DB17942
    Experimental

    RGX-181 consists of an adeno-associated virus serotype 9 (AAV9) vector designed to deliver the soluble lysosomal enzyme tripeptidyl peptidase I (TPP1) gene. … Developed by REGENXBIO, it is being investigated for the treatment of late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease.[L47072]

  7. Drug

    Bacillus calmette-guerin substrain connaught live antigen

    go.drugbank.com/drugs/DB10804
    ApprovedInvestigationalWithdrawn

    It is prepared from the Connaught strain of Bacillus Calmette and Guérin. … Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder and for the prophylaxis of primary

  8. Target

    Retinoic acid-induced protein 3

    go.drugbank.com/bio_entities/BE0000697
    TargetHumans

    Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells.

    Synonyms: G protein-coupled receptor family C group 5 member A
  9. Target

    VLA-4 (very late antigen-4)

    go.drugbank.com/bio_entities/BE0010014
    TargetHumans

    May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, serves as a platform for SRC activation or inactivation. … Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin.

    Synonyms: Fibronectin receptor subunit beta
  10. Target

    NACHT, LRR and PYD domains-containing protein 3

    go.drugbank.com/bio_entities/BE0010347
    TargetHumans

    Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis (PubMed:16407889, PubMed:1840367...

    Synonyms: Angiotensin/vasopressin receptor AII/AVP-like