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Frespaciguat
go.drugbank.com/drugs/DB21683InvestigationalFrespaciguat is under investigation in clinical trial NCT05612035 (Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With … Frespaciguat is a small molecule drug. The usage of the INN stem '-ciguat' in the name indicates that Frespaciguat is a guanylate cyclase activator and stimulator.
PDPSC18
go.drugbank.com/drugs/DB05167ExperimentalPDPSC18 is therapeutic DNA vaccine designed to fight chronic infections with the Hepatitis B virus, entering phase I clinical trials.
Clocapramine
go.drugbank.com/drugs/DB09003ExperimentalClocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia. … In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic.
alpha-Amyl cinnamaldehyde
go.drugbank.com/drugs/DB14175Approvedalpha-Amyl cinnamaldehyde has a jasmine-like odor and is a widely used synthetic fragrance & suspected allergen. It is used in allergenic testing.
Nitroarginine
go.drugbank.com/drugs/DB04223InvestigationalNitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in brain energy and ammonia metabolites. (Neurochem Res 1995:200(4):451-6) … An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity.
Synonyms: N(gamma)-nitro-L-arginineAnser anser feather
go.drugbank.com/drugs/DB10422ApprovedAnser anser feather is used in allergenic testing.
Categories: Non-Standardized Feather Allergenic ExtractThyme
go.drugbank.com/drugs/DB10983ApprovedThyme allergenic extract is used in allergenic testing.
Categories: Non-Standardized Food Allergenic ExtractNavitoclax
go.drugbank.com/drugs/DB12340InvestigationalNavitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, … Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of lymphomas and other types of cancer.
Synonyms: (R)-4-(3-Morpholin-4-Yl-1-Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex-1-Enylmethyl]-Piperazin-1-Yl}-Benzoyl)-3-TrifluoromethanesulfonylbenzenesulfonamideTSHA-118
go.drugbank.com/drugs/DB16996ExperimentalTSHA-118 is a self-complementary AAV9 gene replacement therapy designed to express a human codon-optimized CLN1 transgene for the treatment of CLN1 disease.