Search

Displaying results 641 - 650 of 7056 in total
  1. Drug

    Lactulose

    go.drugbank.com/drugs/DB00581
    ApprovedInvestigational

    Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic … Organization's List of Essential Medicines as one of the most effective and safe medicines employed in a health system[L6205], data regarding its optimal place in therapy is often ambiguous.

    Products: LACTULOSE AL SIRUP
  2. Drug

    Fulvestrant

    go.drugbank.com/drugs/DB00947
    ApprovedInvestigational

    It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. … While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative

    Products: Act Fulvestrant
  3. Drug

    Pirfenidone

    go.drugbank.com/drugs/DB04951
    ApprovedInvestigational

    Pirfenidone is a synthetic pyridone drug. … [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that is used to treat idiopathic pulmonary fibrosis (IPF),[L26801] which is a chronic, progressive form

    Products: Pirfenidone Aet
  4. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … It was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002].

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Aj-vinorelbine
  5. Drug

    Melperone

    go.drugbank.com/drugs/DB09224
    Investigational

    Recently, it has been studied as a treatment of psychosis related to Parkinson's disease [L1316]. … It has been well established in the treatment of confusion, anxiety, restlessness (particularly in the elderly) and schizophrenia as It is known to be well-tolerated with an excellent safety profile.

    Products: MELPERON AL 25, MELPERON AL 100
  6. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.

    Mixtures: Ag-amoxi Clav, Ag-amoxi ClavSynonyms: AX
  7. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. … It was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.

    Categories: UGT2B7 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: CARBAMAZEPIN AL 200 RETARD, CARBAMAZEPIN AL 400 RETARD
  8. Drug

    Magnesium hydroxide

    go.drugbank.com/drugs/DB09104
    ApprovedInvestigational

    Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. … Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite.

    Mixtures: RELCER GEL, DI-GEL LIQUIDO
  9. Drug

    Ipratropium

    go.drugbank.com/drugs/DB00332
    ApprovedInvestigational

    Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent. … [A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption.

    Products: Aa-ipravent, A-TROFINSA
  10. Drug

    Trazodone

    go.drugbank.com/drugs/DB00656
    ApprovedInvestigational

    [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms, or insomnia, which are commonly associated with SSRI and SNRI therapy. … [T646] Trazodone acts on various receptors, including certain histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a narrow range of neurotransmitters

    Synonyms: 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneProducts: Ag-trazodone